Results 81 to 90 of about 142,714 (313)

Nonlinear Photonic Crystals: IV. Nonlinear Schrodinger Equation Regime

open access: yes, 2005
We study here the nonlinear Schrodinger Equation (NLS) as the first term in a sequence of approximations for an electromagnetic (EM) wave propagating according to the nonlinear Maxwell equations (NLM).
Babin, Anatoli, Figotin, Alexander
core   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

open access: yesAdvanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma   +18 more
wiley   +1 more source

Nuclear Exportin 1 (XPO1) Binds to the Nuclear Localization/Export Signal of the Turnip Mosaic Virus NIb to Promote Viral Infection

open access: yesFrontiers in Microbiology, 2022
The nuclear localization signal (NLS) and nuclear export signal (NES) are key signatures of proteins for controlling nuclear import and export. The NIb protein of turnip mosaic virus (TuMV) is an RNA-dependent RNA polymerase (RdRP) that is absolutely ...
Mingzhen Zhang   +11 more
doaj   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

open access: yesAdvanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang   +10 more
wiley   +1 more source

Predicting rogue waves in random oceanic sea states [PDF]

open access: yes, 2004
Using the inverse spectral theory of the nonlinear Schrodinger (NLS) equation we correlate the development of rogue waves in oceanic sea states characterized by the JONSWAP spectrum with the proximity to homoclinic solutions of the NLS equation.
Islas, Alvaro, Schober, Constance
core   +4 more sources

Three-dimensional rogue waves in non-stationary parabolic potentials

open access: yes, 2010
Using symmetry analysis we systematically present a higher-dimensional similarity transformation reducing the (3+1)-dimensional inhomogeneous nonlinear Schrodinger (NLS) equation with variable coefficients and parabolic potential to the (1+1)-dimensional
Akhmediev, N.   +2 more
core   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang   +6 more
wiley   +1 more source

New geometries associated with the nonlinear Schr\"{o}dinger equation

open access: yes, 2001
We apply our recent formalism establishing new connections between the geometry of moving space curves and soliton equations, to the nonlinear Schr\"{o}dinger equation (NLS).
Balakrishnan, Radha, Murugesh, S.
core   +1 more source

CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang   +11 more
wiley   +1 more source

Crystallographic data of an importin-α3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal

open access: yesData in Brief, 2023
53BP1 (TP53-binding protein 1), a key player in DNA double-strand break repair, has a classical bipartite nuclear localization signal (NLS) of sequence 1666-GKRKLITSEEERSPAKRGRKS-1686 that binds to importin-α, a nuclear import adaptor protein ...
Yoshiyuki Matsuura
doaj  

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