Results 21 to 30 of about 773 (139)

NME proteins regulate class switch recombination

FEBS Letters, Volume 593, Issue 1, Page 80-87, January 2019., 2019
Class switch recombination (CSR) in B cells involves deletion‐recombination at switch (S) region DNA and is important for the diversification of antibody isotypes during an immune response. Here, we identify two NME [NM23/NDPK (nucleoside diphosphate kinase)] isoforms, NME1 and NME2, as novel players in this process.
Simin Zheng, Anthony Kusnadi, Jee Eun Choi, Bao Q. Vuong, Daniela Rhodes, Jayanta Chaudhuri   +5 more
wiley   +1 more source

Correlation between negative expression of pepsinogen C and a series of phenotypic markers of gastric cancer in different gastric diseases

Cancer Medicine, Volume 7, Issue 8, Page 4068-4076, August 2018., 2018
Combined detection of negative marker PGC and positive markers MG7‐ Ag and MMP9 could be used as a potential follow‐up panel for monitoring dynamical progression of AG and improve the detection efficiency of high‐risk individuals of gastric cancer, so then to take the necessary interventions on the target population. Abstract Gastric tumorigenesis is a
Jingyi Jiang, Shixuan Shen, Nannan Dong, Jingwei Liu, Qian Xu, Liping Sun, Yuan Yuan   +6 more
wiley   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Mix and match of the tumor metastasis suppressor Nm23 protein isoforms in vitro and in vivo

The FEBS Journal, Volume 285, Issue 15, Page 2856-2868, August 2018., 2018
The two main Nm23 isoforms, Nm23‐H1 and Nm23‐H2, are hexameric enzymes involved in various cellular processes. They exhibit high sequence homology, but are mostly studied as separate genes. Here, we show that endogenous Nm23 proteins are predominantly present as heterohexameric complexes following stochastic association. The stoichiometric distribution
Clement M. Potel, Domenico Fasci, Albert J.R. Heck   +2 more
wiley   +1 more source

Transcriptome Analysis of Platelet‐Rich Plasma–Treated Osteoarthritic Chondrocyte

BioMed Research International, Volume 2024, Issue 1, 2024.
As a blood‐derived biomaterial, platelet‐rich plasma (PRP) has been considered a potential therapy and tried in knee and hip osteoarthritis with beneficial effects as an anti‐inflammatory and potent regenerative agent. To better understand the substantial effect of PRP on chondrocytes in an inflammatory environment, we analyzed the transcriptome ...
Dae Keun Suh, Woo Jin Yeo, Kuhoang Cheong, Jae-Won Heo, Dong Hyeon Kim, Soo Mi Lee, Yong-Soo Lee, Dong Won Suh, Saeed Mohammadi   +8 more
wiley   +1 more source

Differentially expressed and survival‐related proteins of lung adenocarcinoma with bone metastasis

Cancer Medicine, Volume 7, Issue 4, Page 1081-1092, April 2018., 2018
Proteomics identified proteins significantly associated with bone metastasis (BM). Online databases and clinical data verified potential predictive and diagnosis biomarkers. The values for drug development and treatment of lung adenocarcinoma with BM.
Mengdi Yang, Yi Sun, Jing Sun, Zhiyu Wang, Yiyi Zhou, Guangyu Yao, Yifeng Gu, Huizhen Zhang, Hui Zhao   +8 more
wiley   +1 more source

Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome–Wide Association Study

Journal of Oncology, Volume 2018, Issue 1, 2018., 2018
NM23 expression is closely associated with hepatocellular carcinoma (HCC) recurrence, but the hereditary factors influencing NM23 levels are unknown. Using public database, the diagnostic value of NM23 in HCC was investigated. A total of 424 hepatitis B virus‐ (HBV‐) related HCC patients were enrolled to perform a genome–wide association study for ...
Chengkun Yang, Chuangye Han, Xiangkun Wang, Xiwen Liao, Xiaoguang Liu, Wei Qin, Long Yu, Guangzhi Zhu, Hao Su, Sicong Lu, Zhiwei Chen, Tingdong Yu, Zhen Liu, Ketuan Huang, Zhengtao Liu, Yu Liang, Jianlu Huang, Tao Peng, Akira Hara   +18 more
wiley   +1 more source

Abstract Book: 25th Congress of the European Hematology Association Virtual Edition, 2020

, 2020
HemaSphere, Volume 4, Issue S1, Page 1-1168, June 2020.
wiley   +1 more source

Nucleoside diphosphate kinase Nm23-M1 involves in oligodendroglial versus neuronal cell fate decision in vitro

Differentiation, 2012
The adult glial progenitor cells were recently shown to be able to produce neurons in central nervous system (CNS) and to become multipotent in vitro. Although the fate decision of glial progenitors was studied extensively, the signals and factors which regulate the timing of neuronal differentiation still remain unknown.
Owlanj, Hamed, Yang, Hai-Jie, Feng, Zhiwei   +2 more
openaire   +3 more sources

Over-expression of NME/NM23 nucleoside diphosphate kinase 1 in human endometrial cancer.

, 2021
Gynecologic cancers including cancers of the endometrium are a clinical problem (1-4). We mined published microarray data (5, 6) to discover genes associated with endometrial cancers by comparing transcriptomes of the normal endometrium and endometrial tumors from humans.
openaire   +2 more sources