The γ-TuRC: mastermind of multipurpose actions at the centrosome. [PDF]
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Beyond Telomeres: Unveiling the Extratelomeric Functions of TERT in B-Cell Malignancies. [PDF]
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Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs. [PDF]
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Expression of the CXCR4 S338X Variant Improves Anti-Leukemia Efficacy of Anti-CD19 CAR-T Cells. [PDF]
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The Human Nm23/Nucleoside Diphosphate Kinases
Journal of Bioenergetics and Biomembranes, 2000Biochemical experiments over the past 40 years have shown that nucleoside diphosphate (NDP) kinase activity, which catalyzes phosphoryl transfer from a nucleoside triphosphate to a nucleoside diphosphate, is ubiquitously found in organisms from bacteria to human.
M L, Lacombe +4 more
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Nm23/Nucleoside Diphosphate Kinase in Human Cancers
Journal of Bioenergetics and Biomembranes, 2000Tumor metastasis is the leading cause of death in cancer patients. From a series of tumor cohort studies, low expression of Nm23/NDP kinase has been correlated with poor patient prognosis and survival, lymph node infiltration, and histopathological indicators of high metastatic potential in a number of cancer types, including mammary and ovarian ...
M T, Hartsough, P S, Steeg
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Overexpression of nucleoside diphosphate kinase (nm23) in solid tumours
European Journal of Cancer and Clinical Oncology, 1991The product of the nm23-H1 gene, reported to be related to the metastatic potential of tumour cells, was recently identified as the nucleoside diphosphate (NDP) kinase A (Gilles et al., 1991, J Biol Chem, 266, 8784-8789). An analysis of the enzyme by activity measurement and immunological techniques using polyclonal antibodies raised against the NDP ...
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Shrimp oncoprotein nm23 is a functional nucleoside diphosphate kinase
Journal of Bioenergetics and Biomembranes, 2012Biosynthesis of nucleoside triphosphates is critical for bioenergetics and nucleic acid replication, and this is achieved by nucleoside diphosphate kinase (NDK). As an emerging biological model and the global importance of shrimp culture, we have addressed the study of the Pacific whiteleg shrimp (Litopenaeus vannamei) NDK. We demonstrated its activity
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Phosphorylation of NM23/Nucleoside Diphosphate Kinase by Casein Kinase 2 in Vitro
Biochemical and Biophysical Research Communications, 1994We have investigated phosphorylation of human nucleoside diphosphate kinase (NDPK) and of homologous NDPK from different species by human casein kinase 2 (CK-2). The human NDPK isotypes A and B were phosphorylated by CK-2 in vitro both when the purified proteins and total lysate of HL-60 leukemia cells were used. The homologous NDPK's from Yeast and E.
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