Results 121 to 130 of about 154,177 (308)
Slow in Motion but Smart in Learning and Memory: Behavioral Changes in Adult NR3A Knockout Mice [PDF]
, 2011 The expression of NMDA receptor subunit NR3A is high in the neonatal brain but low in adults. However, its functional role in the adult brain is obscure.
Shan Ping Yu +3 more
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Bilateral detection, prediction, and lateralization of seizures using white matter
Epilepsia Open, EarlyView.Abstract Objective To determine how the corpus callosum handles interhemispheric seizure propagation and to assess its potential as a strategic recording locus for state‐dependent biomarkers. Methods Epileptiform activity was induced in vitro and in vivo using 4‐aminopyridine. Propagation dynamics were examined using cross‐correlation analysis.
Nrupen Pakalapati +3 more
wiley +1 more source
Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen +10 more
wiley +1 more source
Neuroscience ResearchNMDA and AMPA receptors are co-localized at most glutamatergic synapses, where their numbers and distribution undergo dynamic changes. Glutamate binds to both the NMDA and AMPA receptors.
Qingchen Guo
doaj +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha +6 more
wiley +1 more source
EEG findings in NMDA encephalitis - A systematic review
, 2019 Purpose: The clinical utility of EEG in cases of NMDA encephalitis is broad with many findings indicating not just epileptiform activity but also encephalopathy and potentially providing insights into pathophysiologic mechanisms of disease.
Gillinder, Lisa +4 more
core +1 more source
iNew Medicine, EarlyView.This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin +10 more
wiley +1 more source
Nouvel outil d'optopharmacologie pour l'étude de la diversité fonctionnelle des récepteurs NMDA
NMDA receptors (NMDARs) are glutamate-gated ion channel receptors broadly expressed in the brain and playing crucial roles in synaptic transmission and plasticity.
Sicard, Antoine
core +2 more sources
Participação do sistema glutamatérgico da substância cinzenta periaquedutal dorsolateral na resposta defensiva de ratos submetidos ao teste-reteste no labirinto em cruz elevado [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.The elevated plus-maze (EPM) has been widely used as a tool to understand defensive behavior related to anxiety ...
Kincheski, Grasielle Clotildes
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Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons
, 2006 We have previously shown that activation of presynaptic N-methyl-d-aspartate (NMDA) receptors (NMDAR) enhances the amplitude of the presynaptic fibre volley (FV) evoked in Schaffer collateral axons of rat hippocampal slices, by a mechanism independent of
Solís, Jose María +1 more
core +1 more source