Results 131 to 140 of about 110,732 (265)

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Dextromethorphan Hydrobromide‐Bupropion Hydrochloride for Agitation in Dementia: Combination or Two Stand‐Alone Drugs

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Eric E. Brown   +2 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Transcranial direct current stimulation enhances delayed retention after 5 days of lower‐limb motor skill learning

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the 5 day lower‐limb motor skill learning protocol combining ankle visuomotor practice with transcranial direct current stimulation (tDCS). Participants were allocated to motor skill practice with active tDCS over the leg representation of primary motor cortex (SKILL‐STIM), motor skill practice with sham ...
August Lomholt Kvistad   +5 more
wiley   +1 more source

A TREK‐1/AQP4/TRPA1/BDNF Signaling Axis Is Associated With Astrocytic Volume Transients, Synaptic Plasticity, and Spatial Memory

open access: yesGlia, Volume 74, Issue 9, September 2026.
Astrocytic TREK‐1‐dependent volume transients contribute to hippocampal synaptic plasticity and memory formation. TRPA1‐mediated astrocytic calcium signaling is required for long‐term potentiation, while astrocytic BDNF is necessary and sufficient to support sustained synaptic plasticity.
Victor James Drew   +6 more
wiley   +1 more source

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