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Distinct pharmacological and functional properties of NMDA receptors in mouse cortical astrocytes [PDF]
British Journal of Pharmacology, 2011 Background and purpose Astrocytes of the mouse neocortex express functional NMDA receptors which are not blocked by Mg2+ions. However, study of the pharmacological profile of glial NMDARs and their subunit composition is far from complete ...
Oleg Palygin +2 more
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Down-regulation of NMDA receptor activity by NMDA
Neuroscience Letters, 1993Rat cerebellar granule cells were cultured in a medium containing 25 mM KCl. The presence of NMDA during culture caused strong down-regulation of 45Ca uptake through the NMDA receptor channel. The process affected neither the viability nor the protein content of the cells. The developmental program of NMDA receptor activity was resumed after removal of
Y, Oster, M, Schramm
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The Neuroscientist, 2007
The amino acid L-Glutamate acts as the most ubiquitous mediator of excitatory synaptic transmission in the central nervous system. Glutamatergic transmission is central for diverse brain functions, being particularly important for learning, memory, and cognition.
Verkhratsky, Alexei; id_orcid 0000-0003-2592-9898 +1 more
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The amino acid L-Glutamate acts as the most ubiquitous mediator of excitatory synaptic transmission in the central nervous system. Glutamatergic transmission is central for diverse brain functions, being particularly important for learning, memory, and cognition.
Verkhratsky, Alexei; id_orcid 0000-0003-2592-9898 +1 more
openaire +4 more sources
Retinogeniculate transmission by NMDA and non-NMDA receptors in the cat
Brain Research, 1991The contributions of N-methyl-D-aspartate (NMDA) and non-NMDA excitatory amino acid (EAA) receptors to retinogeniculate transmission were investigated in the cat. The EAA antagonists 2-amino-5-phosphonovaleric acid (APV) and kynurenic acid (KYN) were used to block the NMDA receptors and all EAA receptors, respectively.
K, Funke, U T, Eysel, T, FitzGibbon
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Implication of non-NMDA and NMDA receptors in cochlear ischemia
NeuroReport, 1992We have investigated the hypothesis that the acute ischemic swelling of the radial dendrites connected to the inner hair cells (IHCs) is mediated by glutamatergic receptors. In control cochleas, after 20 min ischemia all the dendrites were dramatically swollen.
R, Pujol, J L, Puel, M, Eybalin
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