Results 61 to 70 of about 110,343 (264)

Effect of acetaminophen use on GABA, NMDA, and synaptic plasticity-related genes in the immature mouse brain: A preliminary study

open access: yesThe EuroBiotech Journal
Background/aim: Acetaminophen is frequently used as an analgesic during pregnancy. The purpose of the present study was to evaluate the effects of acetaminophen administered to pregnant mice on the fetal brain, attention, memory, and learning functions ...
Göl Mehmet Fatih   +8 more
doaj   +1 more source

Increased serum levels of NMDA receptor antibodies in female patients with bipolar disorder [PDF]

open access: yesKlinik Psikiyatri Dergisi, 2019
Objective: Glutamatergic/GABAergic imbalance due to autoimmune antibodies targeting N-methyl-D-aspartate receptors (NMDA-R) is considered to be one of the shared pathways between bipolar disorder (BD) and autoimmune diseases.
Deniz Ceylan   +6 more
doaj  

Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats

open access: yesJournal of Biomedical Science, 2012
Background Acute exposure of ethanol (alcohol) inhibits NMDA receptor function. Our previous study showed that acute ethanol inhibited the pressor responses induced by NMDA applied intrathecally; however, prolonged ethanol exposure may increase the ...
Keng Nien-Tzu   +4 more
doaj   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-Spikes.

open access: yesPLoS ONE, 2015
Cortical neurons can respond to glutamatergic stimulation with regenerative N-Methyl-D-aspartic acid (NMDA)-spikes. NMDA-spikes were initially thought to depend on clustered synaptic activation.
Alon Poleg-Polsky
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Consumption of Ginkgo biloba Extract and Swimming Training on NMDA and BDNF Plasma in Untrained Girls

open access: yesJournal of Medicinal Plants, 2015
Background: Ginko biloba stimulate blood circulation to the brain. As a result of insufficiency to improve blood flow to the brain. Objective: The aim of this study was to investigate the effect of eight weeks endurance training swimming on BDNF and NMDA
B Hajirezaii, A Barari, A Abbassi Daloii
doaj  

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Endocytosis of GluN2B-containing NMDA receptor mediates NMDA-induced excitotoxicity

open access: yesMolecular Pain, 2017
N-methyl-D-aspartate (NMDA) receptor overactivation is involved in neuronal damage after stroke. However, the mechanism underlying NMDA receptor-mediated excitotoxicity remains unclear.
Yu Wu   +4 more
doaj   +1 more source

No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors

open access: yesTranslational Neurodegeneration, 2019
Background IgG-class autoantibodies to N-Methyl-D-Aspartate (NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis. Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with Parkinson disease with/without ...
Franziska Hopfner   +32 more
doaj   +1 more source

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