Results 71 to 80 of about 298,750 (304)
Nitric oxide and synaptic function [PDF]
, 1994 The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core +1 more source
Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein [PDF]
, 2023 Joana Rajão‐Saraiva +12 more
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Dendritic NMDA spikes are necessary for timing-dependent associative LTP in CA3 pyramidal cells
Nature Communications, 2016 The computational repertoire of neurons is enhanced by regenerative electrical signals initiated in dendrites. These events, referred to as dendritic spikes, can act as cell-intrinsic amplifiers of synaptic input.
Federico Brandalise +4 more
semanticscholar +1 more source
Frontiers in Systems Neuroscience, 2011 Dopamine, via activation of D1 receptors, enhances N-methyl-D-aspartate (NMDA) receptor-mediated responses in striatal medium-sized spiny neurons. However, the role of specific NMDA receptor subunits in this enhancement remains unknown.
Emily L Jocoy +8 more
doaj +1 more source
Pregnane‐based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss‐of‐function disease‐associated GRIN mutations [PDF]
, 2022 Bohdan Kysilov +9 more
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Journal of Neuroscience, 2007 NMDA receptors mediate excitatory postsynaptic potentials throughout the brain but, paradoxically, NMDA receptor antagonists produce cortical excitation in humans and behaving rodents. To elucidate a mechanism for these diverging effects, we examined the
H. Homayoun, B. Moghaddam
semanticscholar +1 more source
Distribution of Extrasynaptic NMDA Receptors on Neurons
The Scientific World Journal, 2012 NMDA receptors are found in both synaptic and extrasynaptic locations on neurons. NMDA receptors also can be found on neurons in early stages prior to synaptogenesis, where they may be involved in migration and differentiation.
Ronald S. Petralia
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Computational study of NMDA conductance and cortical oscillations in schizophrenia
Frontiers in Computational Neuroscience, 2014 N-methyl-D-aspartate (NMDA) receptor hypofunction has been implicated in the pathophysiology of schizophrenia. The illness is also characterized by gamma oscillatory disturbances, which can be evaluated with precise frequency specificity employing ...
Kubra eKomek Kirli +3 more
doaj +1 more source
Journal of Pharmacological Sciences, 2006 .: Generalizations of NMDA-receptor antagonists to the discriminative stimulus effects of κ-opioid receptor agonists in rats were examined. Phencyclidine, MK-801, and ketamine, noncompetitive NMDA-receptor antagonists, generalized to the discriminative ...
Tomohisa Mori +6 more
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Dose-dependent effects of NMDA on retinal and optic nerve morphology in rats [PDF]
International Journal of Ophthalmology, 2019 AIM: To investigate dose-dependent effects of N-methyl-D-aspartate (NMDA) on retinal and optic nerve morphology in rats. METHODS: Sprague Dawley rats, 180-250 g in weight were divided into four groups.
Lidawani Lambuk +7 more
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