Results 151 to 160 of about 22,217 (292)

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

Psychiatry and Clinical Neurosciences, Volume 76, Issue 12, Page 620-632, December 2022., 2022
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more likely to appear in SD than in early‐life depression, but it remains unclear whether the pathophysiology is different. The prevalence of dementia increases with aging, and the underlying pathophysiological processes in the preclinical phase begin even before ...
Ito Kawakami, Jun‐ichi Iga, Sho Takahashi, Yi‐Ting Lin, Hiroshige Fujishiro   +4 more
wiley   +1 more source

Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury

, 1992
Jean R. Wrathall, Yang D. Teng, David Choiniere, Diane J. Mundt   +3 more
openalex   +1 more source

Reduction of NMDA receptors with dithiothreitol increases [³H]‐MK‐801 binding and NMDA‐induced Ca²⁺ fluxes [PDF]

, 1990
Ian J. Reynolds, Elizabeth A. Rush, Elias Aizenman   +2 more
openalex   +1 more source

Prevalence of potentially inappropriately prescribed medications among older adults receiving peritoneal dialysis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Introduction The prevalence of exposure to supratherapeutic doses or contraindicated medications based on renal dosing criteria, also known as potentially inappropriately prescribed medications (PIPM), is currently unknown among patients on peritoneal dialysis (PD).
Armando Silva Almodovar, Macarius Donneyong, Eric Seiber, Milap C. Nahata   +3 more
wiley   +1 more source

Chronic pain management in a dairy cow with deep digital sepsis

Veterinary Record Case Reports, EarlyView.
Abstract This case report describes a cow with a penetrating foreign body in the sole horn of its medial claw of the right forelimb, leading to sequestration and necrosis of the pedal bone and subsequent chronic pain. The surgical interventions, multimodal pain management and development of the gait pattern over more than 6 weeks are described. The cow
Jasmin Laschinger, Johann Kofler
wiley   +1 more source

A caregiver's perspective on clinically relevant symptoms in behavioural variant frontotemporal dementia: tools for disease management and trial design

Psychogeriatrics, Volume 23, Issue 1, Page 11-22, January 2023., 2023
ABSTRACT Background Adequate detection of symptoms and disease progression in behavioural variant frontotemporal dementia (bvFTD) is complex. Dementia cohorts usually utilize cognitive and functional measures, which fail to detect dominant behavioural and social cognitive deficits in bvFTD.
Jay L.P. Fieldhouse, Gaby van Dijk, Freek Gillissen, Marie‐Paule E. van Engelen, Sterre C.M. de Boer, Annemiek Dols, Hendrik‐Jan van der Waal, Barbara J. Regeer, Everard G.B. Vijverberg, Yolande A.L. Pijnenburg   +9 more
wiley   +1 more source

The effect of schizophrenia risk factors on mismatch responses in a rat model

Psychophysiology, Volume 60, Issue 2, February 2023., 2023
Abstract Reduced mismatch negativity (MMN), a robust finding in schizophrenia, has prompted interest in MMN as a preclinical biomarker of schizophrenia. The rat brain can generate human‐like mismatch responses (MMRs) which therefore enables the exploration of the neurobiology of reduced MMRs.
Jaishree Jalewa, Juanita Todd, Patricia T. Michie, Deborah M. Hodgson, Lauren Harms   +4 more
wiley   +1 more source

Selective inhibition of NMDA receptor function by nootropic drugs: evaluation of the sites of action using mRNA-injected Xenopus oocyte responses and [3H]MK-801 binding assay.

, 1991
Shuji Kaneko, Masunobu Sugimura, Hideki Takahashi, Tatsuo Inoue, Masamichi Satoh   +4 more
openalex   +1 more source

The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum [PDF]

, 1993
PW Hickmott, Martha Constantine‐Paton
openalex   +1 more source

Rare but relevant: Nitrous oxide and peripheral neurotoxicity, what do we know?

Addiction, EarlyView.
Abstract Nitrous oxide (N2O), used medically as an anaesthetic, has gained popularity as a recreational drug, with rising prevalence particularly among young adults. While its reinforcing and addictive potential remains debated, N2O is proven to be neurotoxic, especially with prolonged, heavy use, which is often unexpected for users.
Tibor M. Brunt, Wim van den Brink, Jan van Amsterdam   +2 more
wiley   +1 more source