Results 71 to 80 of about 203,682 (360)

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

Age-Dependent, Subunit Specific Action of Hydrogen Sulfide on GluN1/2A and GluN1/2B NMDA Receptors

open access: yesFrontiers in Cellular Neuroscience, 2017
Hydrogen sulfide (H2S) is an endogenously produced neuroactive gas implicated in many key processes in the peripheral and central nervous system. Whereas the neuroprotective role of H2S has been shown in adult brain, the action of this messenger in ...
Aleksey V. Yakovlev   +5 more
doaj   +1 more source

Activation of NMDA receptors in brain endothelial cells increases transcellular permeability

open access: yesFluids and Barriers of the CNS, 2022
Neurovascular coupling is a precise mechanism that induces increased blood flow to activated brain regions, thereby providing oxygen and glucose.
Kyu-Sung Kim   +4 more
doaj   +1 more source

Precocious puberty as a consequence of anti-NMDA receptor encephalitis in children

open access: yesPediatrics and Neonatology, 2021
Background: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is one of the most common autoimmune encephalitis in children. Most children recovered well after anti-NMDA receptor encephalitis.
Po-Ming Wu   +3 more
doaj   +1 more source

Modulating synaptic NMDA receptors [PDF]

open access: yesNeuropharmacology, 2017
Recent structural information on ligand-gated glutamate receptors and newly-discovered clinical uses for NMDA receptor antagonists has renewed interest in understanding the mechanisms of drug action at these receptors. Although the voltage-dependence and calcium permeability of NMDA receptors are well-studied, the mechanisms affecting the time course ...
Kenneth R, Tovar, Gary L, Westbrook
openaire   +2 more sources

Ethanol enhances neurosteroidogenesis in hippocampal pyramidal neurons by paradoxical NMDA receptor activation [PDF]

open access: yes, 2011
Using an antibody against 5α-reduced neurosteroids, predominantly allopregnanolone, we found that immunostaining in the CA1 region of rat hippocampal slices was confined to pyramidal neurons.
Izumi, Yukitoshi   +2 more
core   +2 more sources

TVB C++: A Fast and Flexible Back‐End for The Virtual Brain

open access: yesAdvanced Science, EarlyView.
TVB C++ is a streamlined and fast C++ Back‐End for The Virtual Brain (TVB), designed to make it as flexible as TVB, and FAST. Another pillar is to be fully compatible with TVB so easy bindings can be created from Python. Users can easily configure TVB C++ to execute the same code but with enhanced performance and parallelism.
Ignacio Martín   +7 more
wiley   +1 more source

Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation

open access: yesNeurobiology of Disease, 2003
We analyzed NMDA receptor subunit mRNAs, proteins, and anchoring proteins in mice transgenic for exon 1 of the HD gene. R6/2 mice had decreased levels of mRNAs encoding ε1 and ε2 NMDA receptor subunits (mouse orthologs of rat NR2A and NR2B subunits), but
Ruth Luthi-Carter   +9 more
doaj   +1 more source

Differential expression of GluN2 NMDA receptor subunits in the dorsal horn of male and female rats [PDF]

open access: gold, 2021
Santa Temi   +6 more
openalex   +1 more source

Cortico‐Striatal‐Midbrain Circuit Dysregulation Underlying MK‐801 Induced Impulsivity and the Ameliorative Effects of SEP

open access: yesAdvanced Science, EarlyView.
Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang   +6 more
wiley   +1 more source

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