Results 71 to 80 of about 107,984 (270)
A Mathematical model for Astrocytes mediated LTP at Single Hippocampal Synapses [PDF]
, 2011 Many contemporary studies have shown that astrocytes play a significant role in modulating both short and long form of synaptic plasticity. There are very few experimental models which elucidate the role of astrocyte over Long-term Potentiation (LTP).
arxiv +1 more source
A head start: The relationship of placental factors to craniofacial and brain development
Developmental Dynamics, EarlyView.Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver +2 more
wiley +1 more source
Anti-NMDA-receptor antibody encephalitis in infants
Epilepsy and Behavior Case Reports, 2015 Purpose: Anti-N-methyl-d-aspartate (NMDA) receptor antibody encephalitis is an autoimmune disorder manifesting subacutely with prominent aberrant movements and psychiatric symptoms.
Amr A. Matoq +5 more
doaj +1 more source
Computationally Discovered Potentiating Role of Glycans on NMDA Receptors [PDF]
arXiv, 2016 N-methyl-D-aspartate receptors (NMDARs) are glycoproteins in the brain central to learning and memory. The effects of glycosylation on the structure and dynamics of NMDARs are largely unknown. In this work, we use extensive molecular dynamics simulations of GluN1 and GluN2B ligand binding domains (LBDs) of NMDARs to investigate these effects.
arxiv
Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Epileptic Disorders, EarlyView.Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan +7 more
wiley +1 more source
Age-Dependent, Subunit Specific Action of Hydrogen Sulfide on GluN1/2A and GluN1/2B NMDA Receptors
Frontiers in Cellular Neuroscience, 2017 Hydrogen sulfide (H2S) is an endogenously produced neuroactive gas implicated in many key processes in the peripheral and central nervous system. Whereas the neuroprotective role of H2S has been shown in adult brain, the action of this messenger in ...
Aleksey V. Yakovlev +5 more
doaj +1 more source
Psychosis associated with anti-N-methyl-d-aspartate receptor encephalitis
Open Journal of Psychiatry and Allied Sciences, 2020 Aim: Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is commonly seen in women with various neuropsychiatric symptoms. Here we report a case of psychosis associated with anti-NMDA receptor encephalitis.
Udayan Bhaumik, Hemendra Singh
doaj +1 more source
Paradoxical signaling regulates structural plasticity in dendritic spines [PDF]
, 2016 Transient spine enlargement (3-5 min timescale) is an important event associated with the structural plasticity of dendritic spines. Many of the molecular mechanisms associated with transient spine enlargement have been identified experimentally. Here, we use a systems biology approach to construct a mathematical model of biochemical signaling and ...
arxiv +1 more source
Epileptic Disorders, EarlyView.Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani +8 more
wiley +1 more source
Selective vulnerabilities of N-methyl-D-aspartate (NMDA) receptors during brain aging
Frontiers in Aging Neuroscience, 2010 N-methyl-D-aspartate (NMDA) receptors are present in high density within the cerebral cortex and hippocampus and play an important role in learning and memory.
Brenna L Brim, Siba R Das
doaj +1 more source