Results 31 to 40 of about 406,460 (331)
A Simple Method for the Preparation of 2,4,6-trichloroborazine and Evaluation of 1H-NMR Spectra [PDF]
The compound 2,3,6-trichloroborazine (TCB) is known as a valuable precursor to prepare boron nitride and various derivatives of borazine. Difficulties in the preparation of TCB via conventional methods on the one hand, and its importance for material ...
Aria Norozi +2 more
doaj +1 more source
At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík +9 more
doaj +1 more source
Electroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi +5 more
doaj +1 more source
A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system
Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin‐conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential ...
Sjoerd J L van Wijk +6 more
doaj +1 more source
Effect of charged lipids on the ionization behavior of glutamic acid containing transmembrane helices [PDF]
Transmembrane proteins make up critical components of living cells. Protein function can be greatly impacted by the charged state of its respective components, the side chains of amino acid residues.
Nunn, Brooke
core +2 more sources
High-resolution NMR studies of antibiotics in cellular membranes
Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
João Medeiros-Silva +7 more
doaj +1 more source
Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism [PDF]
The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher ...
Alzyoud, Kholoud S +3 more
core +2 more sources
Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics
Oral cancer is the eighth most common cancer worldwide and represents a significant disease burden. If detected at an early stage, survival from oral cancer is better than 90% at 5 years, whereas late stage disease survival is only 30%.
Stefano Tiziani +2 more
doaj +1 more source
Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows ...
Yanzhang Luo +8 more
doaj +1 more source
High resolution-1Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
Aim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment.
A. V. Mitronin +3 more
doaj +1 more source

