Results 31 to 40 of about 406,460 (331)

A Simple Method for the Preparation of 2,4,6-trichloroborazine and Evaluation of 1H-NMR Spectra [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2022
The compound 2,3,6-trichloroborazine (TCB) is known as a valuable precursor to prepare boron nitride and various derivatives of borazine. Difficulties in the preparation of TCB via conventional methods on the one hand, and its importance for material ...
Aria Norozi   +2 more
doaj   +1 more source

Structural Changes of Sodium Warfarin in Tablets Affecting the Dissolution Profiles and Potential Safety of Generic Substitution

open access: yesPharmaceutics, 2021
At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík   +9 more
doaj   +1 more source

Impacts of Electroconvulsive Therapy on the Neurometabolic Activity in a Mice Model of Depression: An Ex Vivo 1H-[13C]-NMR Spectroscopy Study

open access: yesNeuroglia
Electroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi   +5 more
doaj   +1 more source

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

open access: yesMolecular Systems Biology, 2009
Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin‐conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential ...
Sjoerd J L van Wijk   +6 more
doaj   +1 more source

Effect of charged lipids on the ionization behavior of glutamic acid containing transmembrane helices [PDF]

open access: yes, 2020
Transmembrane proteins make up critical components of living cells. Protein function can be greatly impacted by the charged state of its respective components, the side chains of amino acid residues.
Nunn, Brooke
core   +2 more sources

High-resolution NMR studies of antibiotics in cellular membranes

open access: yesNature Communications, 2018
Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
João Medeiros-Silva   +7 more
doaj   +1 more source

Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism [PDF]

open access: yes, 2017
The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher ...
Alzyoud, Kholoud S   +3 more
core   +2 more sources

Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics

open access: yesNeoplasia: An International Journal for Oncology Research, 2009
Oral cancer is the eighth most common cancer worldwide and represents a significant disease burden. If detected at an early stage, survival from oral cancer is better than 90% at 5 years, whereas late stage disease survival is only 30%.
Stefano Tiziani   +2 more
doaj   +1 more source

Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy

open access: yesNature Communications, 2020
Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows ...
Yanzhang Luo   +8 more
doaj   +1 more source

High resolution-1Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions

open access: yesЭндодонтия Today, 2021
Aim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment.
A. V. Mitronin   +3 more
doaj   +1 more source

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