Results 31 to 40 of about 1,111,397 (348)
Structural basis of death domain signaling in the p75 neurotrophin receptor
eLife, 2015 Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms.
Zhi Lin +6 more
doaj +1 more source
Analysis of Cross-species Anatomical Connection Differences Between Human and Macaque Broca Region
Taiyuan Ligong Daxue xuebao, 2021 On the basis of the idea of comparative neuroscience, the brain atlas registration method was used to extract Broca target brain regions and 10 regions of interest from each subject brain of humans and macaques, and a connectivity fingerprint was ...
Kaixin REN +4 more
doaj +1 more source
, 2010 Tables of 1H and 13C NMR chemical shifts have been compiled for common organic compounds often used as reagents or found as products or contaminants in deuterated organic solvents.
Gregory R. Fulmer +7 more
semanticscholar +1 more source
Protein in-cell NMR spectroscopy at 1.2 GHz
Journal of Biomolecular NMR, 2021 In-cell NMR spectroscopy provides precious structural and functional information on biological macromolecules in their native cellular environment at atomic resolution.
E. Luchinat +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Synthesis and Characterization of Mannich base Derivative from benzotriazole [PDF]
Kirkuk Journal of Science, 2016 This study include prepared number of new Mannich bases derived from equivalent moles p-hydroxybenzaldehyde with equivalent moles from benzotriazole and primary amines in the ethanol as a solvent.
Fariq Salah Ahmed +2 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
A QUANTUM CHEMICAL STUDY OF SMALL MOLECULES USED AS ACTIVE LAYER COMPONENT OF ORGANIC SOLAR CELLS
Momento, 2020 Organic solar cells (OSCs) are one of the best alternatives in the photovoltaic area. These devices convert directly sunlight into electrical current with reasonable efficiencies. The most important component of an OSC is the photoconductive active layer
Haci Baykara +3 more
doaj +1 more source
NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
Bioinform., 2014 Summary: SPARKY (Goddard and Kneller, SPARKY 3) remains the most popular software program for NMR data analysis, despite the fact that development of the package by its originators ceased in 2001.
Woonghee Lee, M. Tonelli, J. Markley
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper +5 more
wiley +1 more source