Results 21 to 30 of about 880,423 (146)
Antioxidants, 2021 Chronic kidney disease (CKD) usually causes devastating healthy impacts on patients. However, the causes affecting the decline of kidney function are not fully revealed, especially the involvement of environmental pollutants.
Chia-Fang Wu +5 more
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Safety Evaluation for Restorin® NMN, a NAD+ Precursor
Frontiers in Pharmacology, 2021 NAD+ is an abundant molecule in the body and vital to all living cells. NAD+ levels decline with age, and this decline correlates with age-related diseases. Therefore, sustaining NAD+ levels offers potential benefits to healthspan and longevity.
John Turner +3 more
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Toxicity and Hypolipidemic Activity of Lansiumamide B in Mice [PDF]
Shipin KexueObjective: To explore the hypolipidemic activity and toxic side effect of lansiumamide B (LB) from chicken-heart shaped wampee (Clausena lansium) seeds in C57BL/6J mice fed on a high-fat-diet (HFD) model.
CHEN Danni, WANG Sainan, YIN Zhaochun, XU Zewen, GUO Xiaomin, LI Kangyuan, WANG Jiawei, CHEN Liping, CAO Yong, XIAO Suyao
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Subacute oral toxicity and bacterial mutagenicity study of Korean Red Ginseng oil
Journal of Ginseng Research, 2017 Background: Red ginseng oil (RGO) is produced by supercritical CO2 extraction of secondary products derived from Korean Red Ginseng extract. As the use of RGO has increased, product safety concerns have become more important.
Hwi Won Seo +5 more
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Scientific Reports, 2022 Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody recognizing glypican-3 and CD3, is in phase I clinical trials. After a first-in-human clinical trial of an anti-CD28 agonist monoclonal antibody resulting in severe life ...
Shun-ichiro Komatsu +14 more
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Molecules, 2018 Gelidium elegans extract (GEE) is derived from a red alga from the Asia–Pacific region, which has antioxidant, anti-adipogenic, and anti-hyperglycemic effects. However, detailed studies of the toxicology of GEE have not been performed.
Jia Choi +5 more
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Safety evaluation of enriched fraction from leaves of Dillenia indica L. in BALB/c mice
Toxicology Reports, 2022 The enriched fraction derived from Dillenia indica L. (Dilleniaceae), also known as elephant apple was subjected to acute and sub-acute toxicological study to document its safety issues for use as fumigant. The enriched fractions were orally administered
Kabrambam D. Singh +8 more
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Safety assessment of (S)-Equol: Subchronic toxicity study in Sprague Dawley Rats
Toxicology Reports(S)-Equol is a chemically synthesized nutraceutical compound and its consumption provides several health benefits for humans. The new nutraceutical, enantiopure (S)-Equol was studied for acute and sub-chronic toxicity in Sprague Dawley Rats.
Seethakallu Ramachandraiah AnandaKumar +2 more
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Risk Assessment of Isoeugenol in Food Based on Benchmark Dose—Response Modeling
Toxics, 2023 Isoeugenol has recently been evaluated as possibly carcinogenic (Group 2B) by the WHO International Agency for Research on Cancer (IARC). In light of this evaluation, an updated risk assessment of this common food constituent was conducted using the ...
Thomas Quentin +2 more
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A No Observable Adverse Effects Level (NOAEL) for pigs fed melamine and cyanuric acid
Regulatory Toxicology and Pharmacology, 2011 Ingesting melamine adulterated milk products led to kidney stones in many infants in 2008. This differs from the renal failure caused by intratubular crystal formation after co-ingestion of melamine (MEL) and cyanuric acid (CYA) in adulterated pet foods in 2007.
Stine, Cynthia B. +9 more
openaire +2 more sources