Results 31 to 40 of about 880,423 (146)
Acute and subchronic oral toxicity study of Camelina sativa oil in Wistar rats
HeliyonObjective: The aim of these studies was to ascertain if Camelina sativa oil is harmful in both the acute and subchronic states. Methods: Wistar rats of both sexes were used in an acute toxicity test, and the fatal dosage (LD50) of oral Camelina sativa ...
Ying Xia +6 more
doaj +1 more source
The Journal of Toxicological Sciences, 2020 Information on the safety of chemical substances in patients with various preexisting conditions remains limited. Acetaminophen was added to the basal diet at 0, 80, 253, 800, 2530, or 8000 ppm and administered to type 2 diabetes mellitus rats (GK/Jcl) and the control male rats (Wistar) for 13 weeks.
Sosuke, Kishi +8 more
openaire +3 more sources
Human Vaccines & Immunotherapeutics, 2021 To compare the safety and immunogenicity of lyophilized PVRV under Zagreb and Essen regimen. A post-marketing parallel control clinical trial was conducted.
Lei Zhang +9 more
doaj +1 more source
Toxicology ReportsFicus erecta leaves, a traditional medicinal plant that is widely used in East Asia, have demonstrated promising cognitive-enhancing effects. However, the safety of its long-term administration has not been elucidated.
Eunjin Sohn +13 more
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26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats
Journal of Pharmacopuncture, 2019 Objectives: KCHO-1(Mecasin), also called Gamijakyakgamchobuja-tang originally, is a combination of some traditional herbal medicines in East Asia. This medicine has been used mainly for alleviating neuropathic pains for centuries in Korean traditional ...
Muhack Yang +10 more
doaj +1 more source
Dietary administration of β-ionone epoxide to Sprague-Dawley rats for 90 days
Current Research in Toxicology, 2021 In a 90-day GLP-compliant study groups of Sprague-Dawley rats (10/sex/group) were fed diets containing β-ionone epoxide, a fragrance material and a flavoring substance, at dietary concentrations providing target intakes of 0, 20, 40 and 80 mg/kg bw/day ...
Vivian Lu +14 more
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Journal of Toxicology, 2023 Soy leghemoglobin (LegH) protein derived from soy (Glycine max) produced in Pichia pastoris (reclassified as Komagataella phaffii) as LegH Prep is a novel food ingredient that provides meat-like flavor and aroma to plant-derived food products. The safety
Teresa F. Reyes +4 more
doaj +1 more source
Assessment of General Toxicity of the Glycyrrhiza New Variety Extract in Rats
Plants, 2021 The Glycyrrhiza radix (Licorice) is one of the most commonly used medicinal plants in Asian countries, such as China, India, and Korea. It has been traditionally used to treat many diseases, including cough, cold, asthma, fatigue, gastritis, and ...
Dong-Gu Kim +9 more
doaj +1 more source
Effect of chronic T-2 toxin exposure in rabbit bucks, determination of the No Observed Adverse Effect Level (NOAEL) [PDF]
Animal Reproduction Science, 2013 T-2 toxin (T-2) was administered to adult Pannon White (n = 10/group) male rabbits for 65 days, first in a suspension by gavage (0.05, 0.1 or 0.2 mg/animal/day), and secondly mixed into the feed (0.33 and 0.66 mg/kg feed). In the first experiment 0.1 mg T-2 exposure resulted in temporary decrease in feed intake, slower increase in the gonadotropin ...
Kovács, Melinda +9 more
openaire +2 more sources
Frontiers in ToxicologyThe CLARITY-BPA Core Study is the most comprehensive animal study of oral bisphenol A (BPA) exposure to date. Rats were exposed daily, in utero until postnatal day 21 or for the animals’ lifetime.
Melissa Badding +2 more
doaj +1 more source