Results 91 to 100 of about 6,271 (203)

Pemanfaatan Ekstrak Khamir Phaffia Rhodozyma Sebagai Sumber Karotenoid Pada Penghambatan Tirosinase [PDF]

open access: yes, 2017
Ekstrak khamir Phaffia rhodozyma mengandung senyawa karotenoid berupa astaxhantin yang memiliki aktivitas sebagai penghambat tirosinase. Senyawa ini dapat menghambat tirosinase dalam mekanisme pembentukan melanin.
Rahardhian, M. R. (Muhammad)   +1 more
core  

Effect of Nobiletin on Lipid Metabolism in Rats

open access: yesJournal of Health Science, 2010
Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes and improves hyperglycemia and insulin resistance in obese (ob) diabetic ob/ob mice. We investigated the effects of nobiletin on lipid metabolism and accumulation of body fat in rats.
Eri Nagata   +7 more
openaire   +2 more sources

The Role of Claudins in the Pathogenesis of Dextran Sulfate Sodium-Induced Experimental Colitis: The Effects of Nobiletin

open access: yesBiomolecules
Background: The pathogenesis of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease is not well understood. This study investigated the roles and regulation of the claudin-1, -2, -3, and -4 isoforms in the pathogenesis of ...
Asmaa Al-Failakawi   +3 more
doaj   +1 more source

Studies on the antidepressant-like effect and prokinetic-like effects and the underlying mechanisms of Fructus aurantii and meranzin hydrate [PDF]

open access: yes, 2016
目的:测定代表中药枳壳汤剂抗抑郁促动力(A&P)的吸收成分,初步阐明其A&P特别是抗抑郁的作用机理。 方法:1.含量测定。运用HPLC/MS/MS测定枳壳汤剂在空肠,海马和前额叶皮层吸收成分;2.急性抗抑郁疗效测试。该实验包括枳壳汤剂及其吸收成分水合橙皮内酯的急性抗抑郁疗效测试。该测试包括强迫游泳实验、旷场实验、习得性无助实验和新奇抑制实验;3.水合橙皮内酯的慢性抗抑郁疗效测试。包括强迫游泳实验和旷场实验;4.离体和在体胃肠动力实验;5.抗抑郁机制研究和抗抑郁促动力的共性机制研究 ...
柳进
core  

Kajian Reversibilitas Interaksi Marmin Terhadap Reseptor Histamin H1, Asetilkolin Muskarinik Ach-m3 Dan β2-adrenergik [PDF]

open access: yes, 2014
Previous studies concluded that amarmin(7 - (6 \u27, 7\u27-dihidroxygeranyl-oxy) coumarin) shown to inhibit isolated Guinea-pig tracheal smooth muscle contraction through its effect as an H1and Ach-M3receptor\u27s antagonist.
Anas, Y. (Yance)   +2 more
core  

Nobiletin Inhibition of BK Channels [PDF]

open access: yesBiophysical Journal, 2019
Liang Sun   +2 more
openaire   +1 more source

Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system. [PDF]

open access: yes, 2019
LED-based photoacoustic imaging has practical value in that it is affordable and rugged; however, this technology has largely been confined to anatomic imaging with limited applications into functional or molecular imaging.
Hariri, Ali   +5 more
core  

Protective effect of aqueous extract of the rhizomes of Sansevieria liberica Gérôme and Labroy on carbon tetrachloride induced hepatotoxicity in rats [PDF]

open access: yes, 2012
The ability of an aqueous extract of the rhizomes of Sansevieria liberica to protect against carbon tetrachloride induced liver injury was investigated in Wistar albino rats.
Igboh, Ngozi Mercy   +3 more
core  

Antisolvent precipitation for the synergistic preparation of ultrafine particles of nobiletin under ultrasonication-homogenization and evaluation of the inhibitory effects of α-glucosidase and porcine pancreatic lipase in vitro

open access: yesUltrasonics Sonochemistry
To further enhance the application of nobiletin (an important active ingredient in Citrus fruits), we used ultrasonic homogenization-assisted antisolvent precipitation to create ultrafine particles of nobiletin (UPN).
Xiaonan Zhang   +8 more
doaj   +1 more source

Nobiletin restores HFD-induced enteric nerve injury by regulating enteric glial activation and the GDNF/AKT/FOXO3a/P21 pathway

open access: yesMolecular Medicine
Background To explore whether nobiletin has a protective effect on high-fat diet (HFD)-induced enteric nerve injury and its underlying mechanism. Methods An obesity model was induced by a HFD.
Yueshan Pang   +5 more
doaj   +1 more source

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