Results 71 to 80 of about 4,723 (202)

Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer

Scientific Reports, 2021
Skin cancer is one of the most dangerous diseases, leading to massive losses and high death rates worldwide. Topical delivery of nutraceuticals is considered a suitable approach for efficient and safe treatment of skin cancer.
Mahitab Bayoumi, Mona G. Arafa, Maha Nasr, Omaima A. Sammour   +3 more
doaj   +1 more source

Nobiletin Inhibits Inflammatory Reaction in Interleukin-1β-Stimulated Human Periodontal Ligament Cells

Pharmaceutics, 2021
The immune response in periodontal lesions is involved in the progression of periodontal disease. Therefore, it is important to find a bioactive substance that has anti-inflammatory effects in periodontal lesions. This study aimed to examine if nobiletin,
Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo   +3 more
doaj   +1 more source

Green Synthesis of Silver Nanoparticles Using Root Extract of Gomphrena vaga Mart.: Metabolomic Insights Into Nanoparticle Formation and Antimicrobial Activity

Nano Select, Volume 7, Issue 8, August 2026.
This study presents the green synthesis of ultrasmall silver nanoparticles using Gomphrena vaga Mart. root extract. The nanoparticles synthesized were stable and showed good broad‐spectrum antibacterial activity against Gram‐positive and Gram‐negative bacteria in initial studies.
Uedson da Silva das Neves, Thyerre Santana da Costa, Symone Costa de Castro, Maelson Cardoso Lacerda, Mauro Alves Bueno, Ljubica Tasic   +5 more
wiley   +1 more source

VALIANT: A Vision‐Authenticity Language Framework Through Integrated Experts and Aligned Numerical‐Textual Descriptors for Citri Reticulatae Pericarpium

Advanced Intelligent Systems, Volume 8, Issue 7, July 2026.
Visual features, numerical descriptors, and controlled textual attributes extracted from smartphone images of Chenpi are integrated by VALIANT, a tailored multimodal framework for simultaneous storage‐age classification and authenticity verification. The workflow distinguishes genuine products from suspicious standard operating procedure mimics while ...
Simon C. K. Chan, Bingxin Huang, Hannah H. Kim, Wentao Yu, Yinqian Luo, Terence T. W. Wong   +5 more
wiley   +1 more source

Nobiletin Inhibits Hepatic Lipogenesis via Activation of AMP-Activated Protein Kinase [PDF]

, 2018
We aimed to investigate the effects of nobiletin on hepatic lipogenesis in high glucose-induced lipid accumulation in HepG2 cells. Nobiletin, a citrus polymethoxyflavonoid with six methoxy groups, is present abundantly in the peels of citrus fruits ...
Jinwoo Yang, Jeehye Sung, Younghwa Kim, Taewon Yuk, Heon Sang Jeong, Junsoo Lee   +5 more
core   +1 more source

Comprehensive Phenolic Profiling and Antioxidant Evaluation of Calyx, Rind, and Edible Tissues From Non‐Astringent Persimmons (Diospyros kaki)

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Tissue‐specific phenolic profiling of non‐astringent persimmons (Fuyu and Jiro) reveals substantial differences in phytochemical composition and antioxidant potential. Persimmon calyx exhibits the highest concentrations of bioactive compounds, highlighting its potential as a valuable by‐product for functional food and nutraceutical applications ...
Huiwen Wang, Muhammad Sajid Arshad, Ayesha Siddiqa, Malik Adil Nawaz, Hafiz A. R. Suleria   +4 more
wiley   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Ameliorative Effects of Newly Developed Citrus Hybrid “Mubong” Peel Extract on Experimental Colitis and Gut Microbiota Dysbiosis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
DSS exposure induces severe colitis, causing gut dysbiosis and mucosal inflammation driven by NF‐κB activation and spikes in pathogenic bacteria, TNF‐α, and IL‐6. However, “Mubong” Peel Extract effectively disrupts this inflammatory cascade. By suppressing NF‐κB‐dependent transcriptional activity, the extract mitigates clinical symptoms like colon ...
Awraris Derbie Assefa, Sang Suk Kim, Seung‐Gab Han, YoSup Park, Jee‐Soo Park   +4 more
wiley   +1 more source

Nobiletin affects circadian rhythms and oncogenic characteristics in a cell-dependent manner.

PLoS ONE, 2020
The natural product nobiletin is a small molecule, widely studied with regard to its therapeutic effects, including in cancer cell lines and tumors. Recently, nobiletin has also been shown to affect circadian rhythms via their enhancement, resulting in ...
Sujeewa S Lellupitiyage Don, Kelly L Robertson, Hui-Hsien Lin, Caroline Labriola, Mary E Harrington, Stephanie R Taylor, Michelle E Farkas   +6 more
doaj   +1 more source

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

Journal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro, Juan Felipe Grisales‐Mejía, Harlen Gerardo Torres Castañeda, Jose A. Mendiola   +3 more
wiley   +1 more source