Da Yuan Yin Regulates Gut Microbiota and Improves Intestinal Injury in Sepsis
Sepsis mouse model was induced by LPS to investigate the effect of Da Yuan Yin (DYY) in vivo. Hematoxylin–eosin staining showed that DYY could reduce intestinal injury caused by sepsis. In addition, DYY can also inhibit inflammation, apoptosis, and promote cell proliferation in sepsis, and promote the expression of tight junction proteins.
Li Wang +4 more
wiley +1 more source
Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling [PDF]
OBJECTIVE: Dietary flavonoids have long been appreciated in reducing cardiovascular disease risk factors, but their mechanisms of action are complex in nature.
Ali, Marfoua S. +6 more
core +1 more source
This retrospective study demonstrates the therapeutic efficacy of Rikkunshito in neonates with radiologically confirmed gastric volvulus or gastroesophageal reflux disease. Rikkunshito treatment significantly improved weight gain and vomiting frequency without serious adverse events, suggesting it is a safe and effective pharmacologic option.
Toshihiro Nakayama +7 more
wiley +1 more source
Potency of Citrus Peels (Citrus Aurantiifolia (Cristm.) Swingle) Ethanolic Extract as Chemopreventive Agent Through Downregulation of C-myc Expression and Inhibition of 7.12-dimethylbenz[a]antrachene Induced Female Sprague Dawley Rats Breast Cell Proliferation [PDF]
The using of natural-based medicine is growing rapidly in societies. Besides being cheap and affordable, natural-based medicine is relatively safer than the synthetic drugs.
Armandari, I. (Inna) +6 more
core
Anti-amnesic activity of Citrus aurantium flowers extract against scopolamine-induced memory impairments in rats [PDF]
Alzheimer's disease (AD) is a progressive neurological disorder that mostly affects the elderly population. Learning and memory impairment as the most characteristic manifestation of dementia could be induced chemically by scopolamine, a cholinergic ...
Alibabaei, Z. +5 more
core +2 more sources
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. ABSTRACT Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang +5 more
wiley +1 more source
Nobiletin affects circadian rhythms and oncogenic characteristics in a cell-dependent manner.
The natural product nobiletin is a small molecule, widely studied with regard to its therapeutic effects, including in cancer cell lines and tumors. Recently, nobiletin has also been shown to affect circadian rhythms via their enhancement, resulting in ...
Sujeewa S Lellupitiyage Don +6 more
doaj +1 more source
Potensi Kemopreventif Ekstrak Etanolik Kulit Jeruk Keprok (Citrus Reticulata) Pada Karsinogenesis Sel Hepar Tikus Galur Sprague Dawley Terinduksi Dmba [PDF]
Salah satu titik tangkap strategi penemuan agen kemopreventif kanker khususnya kanker hepar adalah melalui penghambatan proliferasi dan penekanan ekspresi onkogen c-Myc. Tangeretin, nobiletin, dan hesperidin adalah beberapa senyawa aktif dari kulit jeruk
Meiyanto, E. (Edy)
core
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit's weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio +2 more
wiley +1 more source

