Results 101 to 110 of about 6,271 (203)

Ferric Citrate Attenuates Cardiac Hypertrophy and Fibrosis in a Rat Model of Chronic Kidney Disease. [PDF]

, 2019
IntroductionChronic kidney disease (CKD) promotes hypertrophy and fibrosis in heart, and increases the risk of cardiovascular mortality. Ferric citrate is a dietary phosphate binder used to control hyperphosphatemia in CKD patients.
Goto, Masaki, Jing, Wanghui, Khazaeli, Mahyar, Lau, Wei Ling, Nunes, Ane CF, Suematsu, Yasunori, Vaziri, Nosratola D   +6 more
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Nobiletin acts as a potential anticancer agent against osteosarcoma by regulating ERK and AKT signaling pathways

Bangladesh Journal of Pharmacology, 2014
The current study was aimed to evaluate the anti-proliferative activity of nobiletin, a flavonoid, on osteosarcoma cell line, SaOS-2. Furthermore, we attempted to investigate the signaling pathways involved in the cell growth inhibition mechanism.
Fu-Wen Niu, Yong-Jie Zhang, Kun Li, Mao-Shu Zhang   +3 more
doaj  

Efek Ekstrak Daun Sirsak (Annona Muricata Linn) Terhadap Profil Lipid Tikus Putih Jantan (Rattus Norvegicus) [PDF]

, 2014
Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To ...
Nugraheni, S. (SA), Rahfiludin, Z. (Zen), Wurdianing, I. (Indrawati)   +2 more
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A protein–miRNA biomic analysis approach to explore neuroprotective potential of nobiletin in human neural progenitor cells (hNPCs)

Frontiers in Pharmacology
Chemical-induced neurotoxicity is increasingly recognized to accelerate the development of neurodegenerative disorders (NDs), which pose an increasing health burden to society.
Sadaf Jahan, Sadaf Jahan, Uzair Ahmad Ansari, Uzair Ahmad Ansari, Ankur Kumar Srivastava, Sahar Aldosari, Sahar Aldosari, Nessrin Ghazi Alabdallat, Nessrin Ghazi Alabdallat, Arif Jamal Siddiqui, Andleeb Khan, Hind Muteb Albadrani, Sana Sarkar, Bushra Khan, Mohd Adnan, Aditya Bhushan Pant, Aditya Bhushan Pant   +16 more
doaj   +1 more source

Nobiletin Increased Cytotoxic Activity Of Doxorubicin On Mcf-7 Cells But Not On T47d Cells [PDF]

, 2011
Nobiletin, a citrus flavonoid, shows strong cytotoxic effect in several cancer cell lines. The aim of this research was to investigate cytotoxic activities of nobiletin alone and in combination with doxorubicin.
Fitriasari, Aditya, Hermawan, Adam, Junedi, Sendy, Meiyanto, Edy, Susidarti, Ratna Asmah   +4 more
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Processing of citrus peel for the extraction of flavonoids for biotechnological applications [PDF]

, 2011
Flavonoids are extra nutritional constituents that naturally occur in small quantities in plants. They are a family of polyphenolic compounds that are widespread in nature and are consumed as part of the human diet in significant amounts.
Mahale, Kiran, Puri, Munish, Verma, Madan Lal   +2 more
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Nobiletin and 3′-Demethyl Nobiletin Activate Brown Adipocytes upon β-Adrenergic Stimulation

Nobiletin and 3′-Demethyl Nobiletin Activate Brown Adipocytes upon β-Adrenergic Stimulation
Brown adipose tissue (BAT) specifically regulates energy expenditure via heat production. Nobiletin (NOB), a natural polymethoxylated flavone present in citrus fruits, can activate thermogenesis in the BAT of high-fat diet-induced obese mice. The activity of BAT is directly regulated by β-adrenergic stimulation.
openaire  

Citrus flavonoids for overcoming breast cancer resistance to methotrexate: identification of potential targets of nobiletin and sinensetin

Discover Oncology
Breast cancer is a potentially fatal illness that affects millions of women worldwide. Methotrexate (MTX) may be beneficial for treating breast cancer; however, high doses and prolonged use can cause drug resistance.
Adam Hermawan, Naufa Hanif, Dyaningtyas Dewi Pamungkas Putri, Nurul Fatimah, Heri Himawan Prasetio   +4 more
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Potential role of nobiletin in Alzheimer’s disease

Journal of Food Bioactives, 2023
Huilin Fang, Lingling Zhang, Hui Zhao
openaire   +1 more source

Cytotoxic properties of the stem bark of Citrus reticulata Blanco (Rutaceae) [PDF]

The bioassay-guided fractionation of the n-hexane extract of Citrus reticulata Blanco (Rutaceae) stem bark yielded scoparone (1), xanthyletin (2), lupeol (3), β-amyrin (4), stigmasterol (5), β-sitosterol (6) and palmitic acid.
Al-Groshi, A, Evans, AR, Martin, C, Nahar, L, Sarker, SD, Tahsin, T, Wansi, JD   +6 more
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