Molecular MedicineBackground To explore whether nobiletin has a protective effect on high-fat diet (HFD)-induced enteric nerve injury and its underlying mechanism. Methods An obesity model was induced by a HFD.
Yueshan Pang +5 more
doaj +1 more source
Bangladesh Journal of Pharmacology, 2014 The current study was aimed to evaluate the anti-proliferative activity of nobiletin, a flavonoid, on osteosarcoma cell line, SaOS-2. Furthermore, we attempted to investigate the signaling pathways involved in the cell growth inhibition mechanism.
Fu-Wen Niu +3 more
doaj
Introduction to the activities of the Regional Associations for Laboratory Animal Science [PDF]
, 2018 わが国には現在11 の地区研究会があり、独自の活動が展開されています。本報では、各地区研究会の間での情報交換、交流などを意図して、平成29 年度の活動について北から順に紹介します。なお、会長、事務局担当者及び講演者、話題提供者の方々のお名前は敬称を省略させていただきました。詳細な内容をご希望の方は各地区研究会の事務局にお問い合わせ下さい。There are eleven Regional Associations for Laboratory Animal Science in Japan, and ...
岡山実験動物研究会,
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Nobiletin and 3′-Demethyl Nobiletin Activate Brown Adipocytes upon β-Adrenergic Stimulation
Nobiletin and 3′-Demethyl Nobiletin Activate Brown Adipocytes upon β-Adrenergic StimulationBrown adipose tissue (BAT) specifically regulates energy expenditure via heat production. Nobiletin (NOB), a natural polymethoxylated flavone present in citrus fruits, can activate thermogenesis in the BAT of high-fat diet-induced obese mice. The activity of BAT is directly regulated by β-adrenergic stimulation.
openaire
Interações frutas/vegetais: fármaco com importância clínica [PDF]
, 2014 Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciada em Ciências da NutriçãoIntrodução: A ação profilática das frutas e vegetais em inúmeras doenças crónicas, como diabetes ...
Tavares, Cíntia Dalila Covêlo Sequeira
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Potential role of nobiletin in Alzheimer’s disease
Journal of Food Bioactives, 2023 Huilin Fang, Lingling Zhang, Hui Zhao
openaire +1 more source
Discover OncologyBreast cancer is a potentially fatal illness that affects millions of women worldwide. Methotrexate (MTX) may be beneficial for treating breast cancer; however, high doses and prolonged use can cause drug resistance.
Adam Hermawan +4 more
doaj +1 more source
Nobiletin Ameliorates Alzheimer's Disease Pathology by Reducing Oxidative Stress and Neuroinflammation Through the AMPK/SIRT1/PGC-1<i>α</i> and PI3K/Akt-CREB-BDNF Pathways in 5XFAD Mice. [PDF]
BiomedicinesBaek H, Park M, Lee HJ.
europepmc +1 more source
Nobiletin Ameliorates Doxorubicin-Induced Nephrotoxicity by Targeting Oxidative Stress, Inflammatory, and Apoptotic Pathways: Combined <i>In Vivo</i> and <i>In Silico</i> Insights. [PDF]
ACS OmegaÇetinkaya S +4 more
europepmc +1 more source
Preliminary Safety Assessment for Mandarin Orange Peel Administration to Dogs Based on Physical Conditions and Blood Examination Parameters. [PDF]
MetabolitesYonezawa T +6 more
europepmc +1 more source