Results 61 to 70 of about 6,271 (203)
Molecules, 2023 Nobiletin is a natural product with multiple physiological activities and is the main ingredient of Pericarpium Citri Reticulatae. We successfully discovered that nobiletin exhibits aggregation induced emission enhancement (AIEE) properties and it has ...
Tingting Jin +5 more
doaj +1 more source
Anti-amnesic activity of Citrus aurantium flowers extract against scopolamine-induced memory impairments in rats [PDF]
, 2014 Alzheimer's disease (AD) is a progressive neurological disorder that mostly affects the elderly population. Learning and memory impairment as the most characteristic manifestation of dementia could be induced chemically by scopolamine, a cholinergic ...
Alibabaei, Z. +5 more
core +2 more sources
Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment [PDF]
, 2020 BACKGROUND: Docetaxel chemotherapy in prostate cancer has a modest impact on survival. To date, efforts to develop combination therapies have not translated into new treatments. We sought to develop a novel therapeutic strategy to tackle chemoresistant
Dufès, Christine +9 more
core +3 more sources
Beneficial effects of a representative flavonoid, nobiletin on cognitive and urinary dysfunctions [PDF]
BIO Web of ConferencesCitrus fruits contain flavonoids that exhibit various physiological activities. They have been utilized as fruits, foods, and supplements that may exert favorable effects on health.
Yamada Shizuo +3 more
doaj +1 more source
Nöroprotektif etkili bir flavonoid : nobiletin
, 2019 Nörodejeneratif hastalıkların tedavisinde flavonoidlerin kullanımı yeni umutlar vaad etmektedir. Nobiletin, narenciye kabuklarında bulunan bir polimetoksi flavonoiddir. Nobiletinin nöroprotektif etkiye sahip olduğu pek çok in vivo ve in vitro araştırma ile ortaya konulmuştur.
Yarım, Gül Fatma +4 more
openaire +2 more sources
Frontiers in Pharmacology, 2019 Osteoarthritis (OA), a common degenerative joint disease, is principally characterized by inflammation and destruction of cartilage. Nobiletin, an extract of the peel of citrus fruits, is known to have anti-inflammatory properties.
Zeng Lin +6 more
doaj +1 more source
Pharmaceutics, 2021 The immune response in periodontal lesions is involved in the progression of periodontal disease. Therefore, it is important to find a bioactive substance that has anti-inflammatory effects in periodontal lesions. This study aimed to examine if nobiletin,
Yoshitaka Hosokawa +3 more
doaj +1 more source
Antioxidant capacities of flavones and benefits in oxidative-stress related diseases [PDF]
, 2015 Flavonoids, a group of secondary metabolites widely distributed in the plant kingdom, have been acknowledged for their interesting medicinal properties.
Alves-Silva, Jorge M. +3 more
core +1 more source
Urinary Metabolites of Nobiletin Orally Administered to Rats
Chemical and Pharmaceutical Bulletin, 2003 During the course of our systematic investigation of the metabolism of flavonoids, the polymethoxyflavone nobiletin, occurring in the fruits of Citrus depressa, was orally administered to rats. The urinary metabolites were separated and identified by three-dimensional HPLC equipped with a photodiode array detector and the structure was determined by ...
Takaaki, Yasuda +6 more
openaire +3 more sources
Scientific Reports, 2021 Skin cancer is one of the most dangerous diseases, leading to massive losses and high death rates worldwide. Topical delivery of nutraceuticals is considered a suitable approach for efficient and safe treatment of skin cancer.
Mahitab Bayoumi +3 more
doaj +1 more source