Results 81 to 90 of about 6,271 (203)

Toxic Effects of Silica Nanoparticles on Zebrafish Embryos and Larvae [PDF]

open access: yes, 2013
Silica nanoparticles (SiNPs) have been widely used in biomedical and biotechnological applications. Environmental exposure to nanomaterials is inevitable as they become part of our daily life.
Duan, Junchao   +8 more
core   +2 more sources

Citrus as a component of the Mediterranean Diet [PDF]

open access: yes, 2016
Citrus are native to southeastern Asia, but are present in the Mediterranean basin for centuries. This group of species has reached great importance in some of the Mediterranean countries and, in the case of orange, mandarin and lemon trees, they found ...
Bernardes, João Pedro   +3 more
core  

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

open access: yes, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto   +10 more
core   +2 more sources

Polo-like kinase 1 as a promising diagnostic biomarker and potential therapeutic target for hepatocellular carcinoma

open access: yesTumor Biology, 2020
Hepatocellular carcinoma is a major cause of cancer mortality worldwide. The outcome of hepatocellular carcinoma depends mainly on its early diagnosis. To date, the performance of traditional biomarkers is unsatisfactory.
Eman H. Yousef   +3 more
doaj   +1 more source

Effect of fish oil intake on glucose levels in rat prefrontal cortex, as measured by microdialysis [PDF]

open access: yes, 2013
Background: Brain glucose sensing may contribute to energy homeostasis control. the prefrontal cortex (PFC) participates in the hedonic component of feeding control.
Andrade, Iracema Senna de   +7 more
core   +3 more sources

Protective effect of nobiletin on isolated human islets survival and function against hypoxia and oxidative stress-induced apoptosis

open access: yesScientific Reports, 2019
Islets transplantation, as a treatment of type 1 diabetes, faces challenges, including the loss of islets in the process of isolation and pre-transplantation due to cellular stresses-induced apoptosis.
Somayeh Keshtkar   +10 more
doaj   +1 more source

Fortifikasi Ekstrak Kulit Jeruk Bali Pada Susu Tinggi Kalsium: Terobosan Baru Dalam Pengatasan Osteoporosis Pada Wanita Menopause, Teruji in Vivo Dan Molecular Docking [PDF]

open access: yes, 2013
Osteoporosis has one of the cause is lack of estrogen hormone. Commonly prevention therapy is by consuming high calcium milk, but it is not effective. Bali orange's peel (Citrus maxima Merr.) is a waste material but contains phytoestrogen according to ...
Dianingati, R. S. (Ragil)   +3 more
core  

Hepatoprotective effect of Nobiletin against 5-fluorouracil induce hepatotoxicity

open access: yesCurrent Research in Pharmacology and Drug Discovery
5-florouracil is a widely used anticancer/anti-metabolite drug used to treat solid tumor like colon cancer, head and neck, rectum, stomach, pancreas and breast cancer; but, it can cause hepatotoxicity by induction of apoptosis through activation of caspases enzymes and oxidative stress.
Safa A. Yahya, Nada N. Al-Shawi
openaire   +3 more sources

Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation

open access: yesBiological and Pharmaceutical Bulletin, 2010
A growing body of evidence suggests that nobiletin (5,6,7,8,3',4'-hexamethoxy flavone) from the peel of citrus fruits, enhances the damaged cognitive function in disease animal models. However, the neuroprotective mechanism has not been clearly elucidated.
Yanji, Cui   +10 more
openaire   +3 more sources

ノビレチンは17型ヘルパーT細胞の分化調節により、実験的自己免疫性脳脊髄炎の発症を抑制する [PDF]

open access: yes, 2021
Multiple sclerosis is an organ-specific autoimmune disease that targets the myelin antigen in the central nervous system. Nobiletin is a dietary polymethoxylated flavonoid found in citrus fruits.
Anzaki, Chieri   +5 more
core  

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