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Drosophila as a Model to Study the Mechanism of Nociception
Frontiers in Physiology, 2022 Nociception refers to the process of encoding and processing noxious stimuli, which allow animals to detect and avoid potentially harmful stimuli. Several types of stimuli can trigger nociceptive sensory transduction, including thermal, noxious chemicals,
Jianzheng He +15 more
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A Multimodal Deep Learning Approach to Intraoperative Nociception Monitoring: Integrating Electroencephalogram, Photoplethysmography, and Electrocardiogram [PDF]
SensorsMonitoring nociception under general anesthesia remains challenging due to the complexity of pain pathways and the limitations of single-parameter methods.
Omar M. T. Abdel Deen +2 more
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Differential Responses of Thalamic Reticular Neurons to Nociception in Freely Behaving Mice
Frontiers in Behavioral Neuroscience, 2016 Pain serves an important protective role. However, it can also have debilitating adverse effects if dysfunctional, such as in pathological pain conditions.
Jeiwon Cho
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Daily rhythm of nociception in rats
Journal of Circadian Rhythms, 2004 Background Many behavioral and physiological variables exhibit daily rhythmicity. Few investigations of the daily rhythmicity in nociception have been conducted, and conflicting results have been obtained.
Jayaprakash S +4 more
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Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report [PDF]
Revista Brasileira de Anestesiologia, 2021 Background: Opioid-free anesthesia decreases the incidence of opioid adverse events, but its optimal antinociceptive depth has not been clearly defined.
Sean Coeckelenbergh, Jean-Pierre Estebe
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In vivo antinociceptive and anti-inflammatory potential of hesperidin and its cyclodextrin inclusion compounds [PDF]
Balneo and PRM Research Journal, 2021 Introduction. This study aims to evaluate the antinociceptive activity on inflammatory and non-inflammatory nociception models, as well as the anti-inflammatory action of hesperidin and its inclusion compounds with beta-cyclodextrin and hydroxypropyl ...
CORCIOVĂ Andreia +5 more
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TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons
Scientific Reports, 2021 Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing ...
Tianci Li +6 more
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eLife, 2023 Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa +7 more
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Frontiers in Systems Neuroscience, 2023 The assessment and management of pain and nociception is very challenging in patients unable to communicate functionally such as patients with disorders of consciousness (DoC) or in locked-in syndrome (LIS).
Estelle A. C. Bonin +17 more
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Optogenetics and photopharmacology in pain research and therapeutics
STEMedicine, 2020 Pain afflicts billions of people worldwide, who suffer especially from long-term chronic pain. This gruelling condition affects the nervous system at all levels: from the brain to the spinal cord, the Dorsal Root Ganglia (DRG) and the peripheral fibres ...
Federico Iseppon, Manuel Arcangeletti
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