Results 1 to 10 of about 69,712 (280)
Wellcome Open Research, 2021 Background: Somatosensation depends on primary sensory neurons of the trigeminal and dorsal root ganglia (DRG). Transcriptional profiling of mouse DRG sensory neurons has defined at least 18 distinct neuronal cell types.
Ana P. Luiz +12 more
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Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report [PDF]
Revista Brasileira de Anestesiologia, 2021 Background: Opioid-free anesthesia decreases the incidence of opioid adverse events, but its optimal antinociceptive depth has not been clearly defined.
Sean Coeckelenbergh, Jean-Pierre Estebe
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TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons
Scientific Reports, 2021 Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing ...
Tianci Li +6 more
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In vivo antinociceptive and anti-inflammatory potential of hesperidin and its cyclodextrin inclusion compounds [PDF]
Balneo and PRM Research Journal, 2021 Introduction. This study aims to evaluate the antinociceptive activity on inflammatory and non-inflammatory nociception models, as well as the anti-inflammatory action of hesperidin and its inclusion compounds with beta-cyclodextrin and hydroxypropyl ...
CORCIOVĂ Andreia +5 more
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Calcium imaging for analgesic drug discovery
Neurobiology of Pain, 2022 Somatosensation and pain are complex phenomena involving a rangeofspecialised cell types forming different circuits within the peripheral and central nervous systems.
Federico Iseppon +2 more
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Pain detection with bioimpedance methodology from 3-dimensional exploration of nociception in a postoperative observational trial [PDF]
, 2020 Although the measurement of dielectric properties of the skin is a long-known tool for assessing the changes caused by nociception, the frequency modulated response has not been considered yet.
Copot, Dana +4 more
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Effects of Δ⁹-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats. [PDF]
, 2021 An inhalation system based on e-cigarette technology produces hypothermic and antinociceptive effects of Δ⁹-tetrahydrocannabinol (THC) in rats. Indirect comparison of some prior investigations suggested differential impact of inhaled THC between Wistar ...
Cole, Maury +4 more
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eLife, 2023 Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa +7 more
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Drosophila as a Model to Study the Mechanism of Nociception
Frontiers in Physiology, 2022 Nociception refers to the process of encoding and processing noxious stimuli, which allow animals to detect and avoid potentially harmful stimuli. Several types of stimuli can trigger nociceptive sensory transduction, including thermal, noxious chemicals,
Jianzheng He +15 more
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Optogenetics and photopharmacology in pain research and therapeutics
STEMedicine, 2020 Pain afflicts billions of people worldwide, who suffer especially from long-term chronic pain. This gruelling condition affects the nervous system at all levels: from the brain to the spinal cord, the Dorsal Root Ganglia (DRG) and the peripheral fibres ...
Federico Iseppon, Manuel Arcangeletti
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