Drosophila as a Model to Study the Mechanism of Nociception
Frontiers in Physiology, 2022 Nociception refers to the process of encoding and processing noxious stimuli, which allow animals to detect and avoid potentially harmful stimuli. Several types of stimuli can trigger nociceptive sensory transduction, including thermal, noxious chemicals,
Jianzheng He +15 more
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Current Methods to Investigate Nociception and Pain in Zebrafish
Frontiers in Neuroscience, 2021 Pain is an unpleasant, negative emotion and its debilitating effects are complex to manage. Mammalian models have long dominated research on nociception and pain, but there is increasing evidence for comparable processes in fish.
Céline Heinl, Lars Lewejohann
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Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray [PDF]
eNeuro, 2017 The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in
Bruchas, Michael R +7 more
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The ankyrin repeat domain of the TRPA protein painless is important for thermal nociception but not mechanical nociception. [PDF]
PLoS ONE, 2012 The Drosophila TRPA channel Painless is required for the function of polymodal nociceptors which detect noxious heat and noxious mechanical stimuli. These functions of Painless are reminiscent of mammalian TRPA channels that have also been implicated in ...
Richard Y Hwang +2 more
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Differential Responses of Thalamic Reticular Neurons to Nociception in Freely Behaving Mice
Frontiers in Behavioral Neuroscience, 2016 Pain serves an important protective role. However, it can also have debilitating adverse effects if dysfunctional, such as in pathological pain conditions.
Jeiwon Cho
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STING controls nociception via type I interferon signalling in sensory neurons
Nature, 2021 Amanda S Andriessen +2 more
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Daily rhythm of nociception in rats
Journal of Circadian Rhythms, 2004 Background Many behavioral and physiological variables exhibit daily rhythmicity. Few investigations of the daily rhythmicity in nociception have been conducted, and conflicting results have been obtained.
Jayaprakash S +4 more
doaj +3 more sources
TRPV1 activity and substance P release are required for corneal cold nociception [PDF]
Nature Communications, 2019 Guo, Changxiong +6 more
core +3 more sources
Animal Models of Nociception [PDF]
Pharmacological Reviews, 2001 Daniel Le Bars +2 more
openalex +2 more sources
Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report [PDF]
Revista Brasileira de Anestesiologia, 2021 Background: Opioid-free anesthesia decreases the incidence of opioid adverse events, but its optimal antinociceptive depth has not been clearly defined.
Sean Coeckelenbergh, Jean-Pierre Estebe
doaj +3 more sources