Results 101 to 110 of about 86,806 (345)

Opioid and Nitrergic Pathways Mediate Antinociception by Pectis elongata Kunth. Essential Oil

Chemistry &Biodiversity, EarlyView.
ABSTRACT In the present study, we aimed to evaluate the antinociceptive potential of the Pectis elongata essential oil (PeEO) and to understand its mechanism of action by identifying possible pain inhibition pathways. PeEO was analyzed using gas chromatography coupled with mass spectrometry.
Angela Palma Amorin, Sandra Layse Ferreira Sarrazin, Leomara Andrade da Silva, Thaiana Neves Coelho, Adriele Pantoja Cunha, Vitória Albuquerque de Lima, Domingas Machado da Silva, Pablo Luis Baia Figueiredo, Ricardo Bezerra de Oliveira   +8 more
wiley   +1 more source

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. [PDF]

, 2012
BackgroundResponding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism. The sensations of small and large changes in temperature in most organisms have been studied separately in the context of ...
Ghosh, Rajarshi, Kruglyak, Leonid, Mohammadi, Aylia, Ryu, William S   +3 more
core   +3 more sources

Effect of Spinally Administered Simvastatin on the Formalin-Induced Nociceptive Response in Mice

Journal of Pharmacological Sciences, 2012
Clinical and experimental observations indicated that 3-hydroxy-3-methylglutaryl CoA reductase inhibitor statins have pleiotropic effects. The present study determined the antinociceptive property of centrally administered simvastatin on the formalin ...
Masahiro Ohsawa, Junpei Mutoh, Shohei Yamamoto, Hideki Ono, Hiroaki Hisa   +4 more
doaj   +1 more source

Quantifying cerebral contributions to pain beyond nociception

Nature Communications, 2017
Cerebral processes contribute to pain beyond the level of nociceptive input and mediate psychological and behavioural influences. However, cerebral contributions beyond nociception are not yet well characterized, leading to a predominant focus on ...
Choong-Wan Woo, L. Schmidt, A. Krishnan, M. Jepma, M. Roy, M. Lindquist, L. Atlas, T. Wager   +7 more
semanticscholar   +1 more source

UPLC–ESI–QToF–MS Profile of Hydroalcoholic Extract of Persea cordata (Meisn.) and its Antioedematogenic and Antinociceptive Effects in Mice

Chemistry &Biodiversity, EarlyView.
Hydroalcoholic crude extract of Persea cordata showed in its composition, the presence of lignans based on LCESIMS data. This crude extract displayed anti‐oedematogenic and antinociceptive activities in vivo. Abstract This study aimed to establish the chemical profile and evaluate the anti‐oedematogenic and analgesic activities of the hydroalcoholic ...
Valfredo Schlemper, Daniela Hemsing, Julia Elisabett K. Bolsonello, Susana R. de Mello Schlemper, Tiago Tizziani, Lutuima A. Capangue Neto, Louis P. Sandjo   +6 more
wiley   +1 more source

5-HT3-Receptor Antagonist Inhibits Visceral Pain Differently in Chemical and Mechanical Stimuli in Rats

Journal of Pharmacological Sciences, 2004
The present study was designed to compare the effects of a selective 5-HT3-receptor antagonist, alosetron, on the glycerol- and colorectal distention (CRD)-induced visceral nociception as measured by changes in EMG of the external oblique muscle in ...
Tomohisa Mori, Ken-ichi Kawano, Takashi Shishikura   +2 more
doaj   +1 more source

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Methods Used to Evaluate Pain Behaviors in Rodents

Frontiers in Molecular Neuroscience, 2017
Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited.
Jennifer R. Deuis, Lucie S. Dvorakova, Irina Vetter, Irina Vetter   +3 more
doaj   +1 more source

Brainstem neuroimaging of nociception and pain circuitries

PAIN Reports, 2019
The brainstem is known to be an important brain area for nociception and pain processing, and both relaying and coordinating signaling between the cerebrum, cerebellum, and spinal cord.
V. Napadow, R. Sclocco, L. Henderson
semanticscholar   +1 more source

Artificial skin sensation for neuroprosthetic hands

FlexMat, EarlyView.
In this review, Li et al. provide a systematic summary of the design strategy and performance of flexible tactile sensors for neuroprosthetic hands, which can efficiently transduce environmental stimuli such as pressure, temperature, and pain. The comparisons of sensing modality between human skin and each flexible sensor subtype are also discussed ...
Yue Li, Tie Li, Ting Zhang, Zheng Liu
wiley   +1 more source