Results 111 to 120 of about 86,806 (345)
The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]
, 2016 Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T. +6 more
core
Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception in Drosophila [PDF]
, 2020 Wan Song +2 more
openalex +1 more source
Journal of clinical monitoring and computing, 2019 Monitors that estimate nociception during anesthesia may be used to guide opioid and other analgesics administration to optimize anesthesia care and possibly outcome.
Fleur S. Meijer +9 more
semanticscholar +1 more source
Research progress on the depth of anesthesia monitoring based on the electroencephalogram
Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley +1 more source
Opioid regulation of Mu receptor internalisation: relevance to the development of tolerance and dependence [PDF]
, 2010 Internalisation of the mu opioid receptor from the surface of cells is generally achieved by receptor occupancy with agonist ligands of high efficacy. However, in many situations the potent analgesic morphine fails to promote internalisation effectively ...
Lopez-Gimenez, J.F., Milligan, G.
core +2 more sources
PLoS ONE, 2015 The present study investigated the effects of the ethanolic extract (ESa), fractions, and compounds isolated from Sinningia aggregata in male Swiss mice on carrageenan-induced paw edema, neutrophil migration, mechanical hyperalgesia, formalin-induced ...
Geórgea V Souza +8 more
doaj +1 more source
Journal of Orthopaedic Research, EarlyView.ABSTRACT Tendinopathy is a complex, painful condition that affects up to 5% of the general population in their lifetime. Antibiotic treatment with fluoroquinolones has been associated with the onset of tendinopathy and tendon rupture. The mechanisms behind fluoroquinolone induced tendinopathy remain unclear. To probe activation of potentially causative
Nicole A. Chittim +4 more
wiley +1 more source
Somatosensory and nociceptive changes in chronic post-stroke shoulder pain [PDF]
, 2008 Preliminary results from a cross-sectional study that investigated the relation between the presence of post-stroke shoulder pain and somatosensory and nociceptive changes are presented.
Buitenweg, J.R. +5 more
core +1 more source
The role of cGMP and PKG-I in spinal nociceptive processing [PDF]
, 2005 First paragraph (this article has no abstract) Persistent stimulation of nociceptors results in sensitization of nociceptive sensory neurons, which is associated with hyperalgesia and allodynia.
Geisslinger, Gerd +5 more
core +1 more source
Impaired pain sensation in mice lacking prokineticin 2
Molecular Pain, 2006 Prokineticins (PKs), consisting of PK1 and PK2, are a pair of newly identified regulatory peptides. Two closely related G-protein coupled receptors, PKR1 and PKR2, mediate the signaling of PKs. PKs/PKRs participate in the regulation of diverse biological
Amadesi Silvia +6 more
doaj +1 more source