Results 121 to 130 of about 87,919 (361)

L-cysteine modulates visceral nociception mediated by the CaV2.3 R-type calcium channels [PDF]

, 2022
Seyed Mohammadreza Ghodsi, MacKenzie Walz, Toni Schneider, Slobodan M. Todorovic   +3 more
openalex   +1 more source

Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori, Cristina Manis, Enrica Spano, Nicola Simola, Alessandro Ieraci, Pierluigi Caboni, Gaetano Di Chiara, Maria Antonietta De Luca   +7 more
wiley   +1 more source

A Multimodal Deep Learning Approach to Intraoperative Nociception Monitoring: Integrating Electroencephalogram, Photoplethysmography, and Electrocardiogram

Sensors
Monitoring nociception under general anesthesia remains challenging due to the complexity of pain pathways and the limitations of single-parameter methods.
Omar M. T. Abdel Deen, Shou-Zen Fan, Jiann-Shing Shieh   +2 more
doaj   +1 more source

Lateral hypothalamic fast-spiking parvalbumin neurons modulate nociception through connections in the periaqueductal gray area

Scientific Reports, 2019
A pivotal role of the lateral hypothalamus (LH) in regulating appetitive and reward-related behaviors has been evident for decades. However, the contributions of LH circuits to other survival behaviors have been less explored. Here we examine how lateral
Justin N. Siemian, Cara B. Borja, Sarah Sarsfield, Alexandre Kisner, Yeka Aponte   +4 more
doaj   +1 more source

Simultaneous impairment of passive avoidance learning and nociception in rats following chronic swim stress

Advanced Biomedical Research, 2016
Background: Stress can alter response to nociception. Under certain circumstances stress enhances nociception, a phenomenon which is called stress-induced hyperalgesia (SIH).
Masoud Nazeri, Mohammad Shabani, Shahrnaz Parsania, Leila Golchin, Moazamehosadat Razavinasab, Fatemeh Abareghi, Moein Kermani   +6 more
doaj   +1 more source

Somatosensory and nociceptive changes in chronic post-stroke shoulder pain [PDF]

, 2008
Preliminary results from a cross-sectional study that investigated the relation between the presence of post-stroke shoulder pain and somatosensory and nociceptive changes are presented.
Buitenweg, J.R., Dongen, R.T.M. van, Geurts, A.C.H., IJzerman, M.J., Renzenbrink, G.J., Roosink, M.   +5 more
core   +1 more source

Advances in understanding nociception and neuropathic pain

Journal of Neurology, 2017
Pain results from the activation of a subset of sensory neurones termed nociceptors and has evolved as a “detect and protect” mechanism. However, lesion or disease in the sensory system can result in neuropathic pain, which serves no protective function.
Ewan St. John Smith
semanticscholar   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Influence of shoulder pain on muscle function: implications for the assessment and therapy of shoulder disorders [PDF]

, 2014
Shoulder pain is often a challenging clinical phenomenon because of the potential mismatch between pathology and the perception of pain. Current evidence clearly emphasizes an incomplete understanding of the nature of shoulder pain. Indeed, the effective
Falla, Deborah, Lluch, Enrique, Meeus, Mira, Nijs, Jo, Noten, Suzie, Struyf, Filip   +5 more
core   +2 more sources

Brainstem neuroimaging of nociception and pain circuitries

PAIN Reports, 2019
The brainstem is known to be an important brain area for nociception and pain processing, and both relaying and coordinating signaling between the cerebrum, cerebellum, and spinal cord.
V. Napadow, R. Sclocco, L. Henderson
semanticscholar   +1 more source