Results 141 to 150 of about 39,072 (265)

Global Burden of Sickle Cell Disease: Adequacy of Pain Control as Evidenced by Frequency of Oral Pain Medication Use, Health Outcomes, and Emotional Well‐Being Across Diverse Populations

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Sickle cell disease (SCD) is a chronic genetic disorder causing severe pain, anemia, and systemic complications that negatively affect patients’ physical and mental well‐being. The aim of this global cross‐sectional study was to evaluate the relationship between oral pain medication (OPM) use frequency and health outcomes ...
Akshat Jain, Lisa Roberts, Safiye Sahin
wiley   +1 more source

Justifying model complexity: Evaluating transfer learning against classical models for intraoperative nociception monitoring under anesthesia. [PDF]

PLoS One
Lee C, Lee J, Vogt KA, Munshi M.
europepmc   +1 more source

Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song, Lin Yuan, Weiguo Yang, Wen Li, Jia‐Yi Li   +4 more
wiley   +1 more source

Influence of a repeated peripheral electrical stimulation on substance P and cortisol concentrations, and behavior in German Simmental calves - a pilot study. [PDF]

Front Vet Sci
Tschoner T, Kerber H, Zablotski Y, Knubben-Schweizer G, Feist M.   +4 more
europepmc   +1 more source

eIF2α phosphorylation controls thermal nociception

, 2016
Arkady Khoutorsky, Robert E. Sorge, Masha Prager‐Khoutorsky, Sophie Anne Pawlowski, Geraldine Longo, Seyed Mehdi Jafarnejad, Soroush Tahmasebi, Loren J. Martin, Mark H. Pitcher, Christos G. Gkogkas, Reza Sharif‐Naeini, Alfredo Ribeiro‐da‐Silva, Charles W. Bourque, Fernando Cerveró, Jeffrey S. Mogil, Nahum Sonenberg   +15 more
openalex   +2 more sources

Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood

British Journal of Pharmacology, Volume 183, Issue 7, Page 1517-1538, April 2026.
Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori, Cristina Manis, Enrica Spano, Nicola Simola, Alessandro Ieraci, Pierluigi Caboni, Gaetano Di Chiara, Maria Antonietta De Luca   +7 more
wiley   +1 more source

Modeling mechanisms of nociception using the African mole-rat family

, 2021
Karlien Debus
openalex   +2 more sources

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Paradoxes weaken the International Association for the Study of Pain definition of pain. [PDF]

Korean J Pain
Cohen ML, Weisman A, Quintner JL.
europepmc   +1 more source

Preventing Postoperative Catheter-Related Bladder Discomfort (CRBD) with Bladder Irrigation Using 0.05% Lidocaine Saline Solution: Monitoring with Analgesia Nociception Index (ANI) after Transurethral Surgery [PDF]

Chia‐Heng Lin, I‐Cheng Lu, Tz‐Ping Gau, Kuang‐I Cheng, Hsin-Ling Chen, Ping‐Yang Hu   +5 more
openalex   +1 more source