Results 151 to 160 of about 87,919 (361)

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Impacts of chronic stress on urinary bladder function & recovery through modification of PACAP signaling [PDF]

, 2016
Stress can cause or contribute to bladder dysfunction though specific effects remain unclear. Individuals with interstitial cystitis (IC)/bladder pain syndrome (BPS) experience increased symptom severity with stress, including pain and increased urgency ...
Mathews, Morgan E
core   +1 more source

‘Back to Basics’: A Self‐Administered Survey of Undergraduate Dentists' Prevalence, Impact and Understanding of Lower Back Pain

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction The aim of this paper is to assess the prevalence, impact, and understanding of Lower Back Pain (LBP) amongst final year dental students to inform the development of a module in the dental curriculum. LBP has a significant impact on the dental workforce; yet little is reported about the profession's knowledge, or the necessity for
Samuel Cope, Elizabeth Willasey, Daniel Dadnam, Laura Gartshore   +3 more
wiley   +1 more source

Entanglement between thermoregulation and nociception in the rat: the case of morphine [PDF]

, 2016
Nabil El Bitar, B. Pollin, Elias G. Karroum, Ivanne Pincedé, Daniel Le Bars   +4 more
openalex   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Decision letter: Steroid hormone signaling activates thermal nociception during Drosophila peripheral nervous system development

, 2022

openalex   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima, Renata Rao, Gyöngyi Szabó, Sebastian Szklener, Cristina Tassorelli, Marcin Nastaj, Denise E. Chou, Ani C. Khodavirdi, Mahan Chehrenama, Yineng Zhu, Ajay K. Bhatia, David W. Dodick   +11 more
wiley   +1 more source

Is the temporomandibular joint affected by rheumatoid arthritis? A comparative investigation with knee arthritis in an experimental rat model

Journal of Anatomy, EarlyView.
Animals were sensitized with mBSA emulsified in CFA/IFA and subsequently received three intra‐articular injections of mBSA into either the TMJ or the knee (once per week). Mechanical hyperalgesia was assessed using electronic von Frey testing after arthritis establishment at 24 h or 7 days following the third intra‐articular injection.
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Delane Viana Gondim   +2 more
wiley   +1 more source

Psychometric Properties of Pain Scales in Inpatient Settings: An Umbrella Review

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To identify the pain assessment scales with the best psychometric properties to be used by nurses in an inpatient setting. Design Umbrella review. Methods A comprehensive search of four databases was conducted for systematic reviews published from July 2013 to November 2024, focusing on psychometric properties of pain scales used in ...
Fabio D'Agostino, Noemi Giannetta, Gianfranco Sanson, Claudia Fantuzzi, Sara Cignola, Manuele Cesare, Daniela D'Angelo, Antonello Cocchieri   +7 more
wiley   +1 more source