Results 161 to 170 of about 86,806 (345)

Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. [PDF]

, 2018
GPR139 is an orphan G protein-coupled receptor (GPCR) that is expressed mainly in the brain, with the highest expression in the medial habenula. The modulation of GPR139 receptor function has been hypothesized to be beneficial in the treatment of some ...
Conlisk, Dana, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kimbrough, Adam, Kononoff, Jenni   +5 more
core  

Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain [PDF]

, 2022
Cindy Guerrero-Toro, Kseniia Koroleva, Elizaveta V. Ermakova, Oleg Gafurov, П. А. Абушик, Pasi Tavi, Г. Ф. Ситдикова, Rashid Giniatullin   +7 more
openalex   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima, Renata Rao, Gyöngyi Szabó, Sebastian Szklener, Cristina Tassorelli, Marcin Nastaj, Denise E. Chou, Ani C. Khodavirdi, Mahan Chehrenama, Yineng Zhu, Ajay K. Bhatia, David W. Dodick   +11 more
wiley   +1 more source

Animal Consciousness [PDF]

, 2018
This chapter addresses the extent to which nonhuman animals are conscious.
Gennaro, Rocco J.
core  

Correlation between incremental remifentanil doses and the Nociception Level (NOL) index response after intraoperative noxious stimuli [PDF]

, 2019
Etienne Renaud‐Roy, Pierre-André Stöckle, Sarah Maximos, Véronique Brulotte, Lucas Sidéris, Pierre Dubé, Pierre Drolet, Issam Tanoubi, Rami Issa, Olivier Verdonck, Louis‐Philippe Fortier, Philippe Richebé   +11 more
openalex   +1 more source

Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation [PDF]

, 2021
Diéssica Padilha Dalenogare, Camila dos Santos Ritter, Fernando Bellinaso, Sabrina Qader Kudsi, Gabriele Cheiran Pereira, Maria Fernanda Pessano Fialho, Débora Denardin Lückemeyer, Caren Tatiane de David Antoniazzi, Lorenzo Landini, Juliano Ferreira, Guilherme Vargas Bochi, Sara Marchesan Oliveira, Francesco De Logu, Romina Nassini, Pierangelo Geppetti, Gabriela Trevisan   +15 more
openalex   +1 more source

Persistent postural‐perceptual dizziness versus vestibular migraine: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This article reviews the differences and similarities between persistent postural‐perceptual dizziness (PPPD) and vestibular migraine. Background PPPD is considered a chronic functional vestibular disorder characterized by persistent dizziness, unsteadiness, nonspinning vertigo, and often exacerbated by upright posture, movement, or ...
David Moreno‐Ajona
wiley   +1 more source

A737 DIFFERENTIAL C-FOS ONCOGENE EXPRESSION IN MECHANICALLY- VERSUS CHEMICALLY-INDUCED VISCERAL NOCICEPTION [PDF]

, 1990
Joyce A. DeLeo, Dennis W. Coombs, Lawrence E. McCarthy   +2 more
openalex   +1 more source

A Neonatal Nurse‐Controlled Model of Analgesia to Manage Post‐Operative Pain in the Surgical Neonate: A Pilot Randomised Controlled Trial

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To test the feasibility and acceptability of a newly developed model of neonatal nurse‐controlled analgesia to manage pain in the post‐operative infant. Design The study utilised a single‐centre two‐arm parallel, unblinded randomised controlled external pilot trial design.
Renee Muirhead, Kathryn Kynoch, Glenda Hawley, Emma Ballard, Pita Birch, P. A. Lewis   +5 more
wiley   +1 more source

Indirect involvement of α2-adrenoceptors in the mechanical antihypersensitivity effect induced by the spinally administered imidazoline I1 receptor ligand LNP599 in a rat model of experimental neuropathy

Brain Research Bulletin
Here we assess whether neuropathic pain hypersensitivity is attenuated by spinal administration of the imidazoline I1-receptor agonist LNP599 and whether the attenuation involves co-activation of α2-adrenoceptors.
Hong Wei, Anne Vuorenpää, Jonne Laurila, Andrii Domanskyi, Ari Koivisto, Antti Pertovaara   +5 more
doaj   +1 more source