Results 171 to 180 of about 87,919 (361)

Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley   +1 more source

Animal Consciousness [PDF]

, 2018
This chapter addresses the extent to which nonhuman animals are conscious.
Gennaro, Rocco J.
core  

Sensory and Sympathetic Nerve Localization in Mouse Temporomandibular Joint and Knee Joint Neuro‐Musculoskeletal Tissues

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Sympathetic‐sensory coupling is increasingly implicated in joint homeostasis and disease. Towards the long‐term goal of deciphering its role in temporomandibular disorders (TMDs), we characterised the spatial relationships of sympathetic and sensory nerves and their receptors in the mouse temporomandibular joint (TMJ) and trigeminal ...
Qianlin Ye, Aida Mohammadi, Xinli Zhang, Karolina Elżbieta Kaczor‐Urbanowicz, Sunil Kapila   +4 more
wiley   +1 more source

Nerve Growth Factor Signaling and Its Contribution to Pain

Journal of Pain Research, 2020
Philip A Barker,1 Patrick Mantyh,2 Lars Arendt-Nielsen,3 Lars Viktrup,4 Leslie Tive5 1Department of Biology, University of British Columbia, Kelowna, BC, Canada; 2Department of Pharmacology, University of Arizona, Tucson, AZ, USA; 3Department of Health ...
Barker PA, Mantyh P, Arendt-Nielsen L, Viktrup L, Tive L   +4 more
doaj  

<i>Macaranga peltata</i> Alleviates Neuropsychiatric Disorders in Mouse Model and Computational Study. [PDF]

Food Sci Nutr
The methanol extract of Macaranga peltata leaves (MEMPL) exhibited notable neuropharmacological and analgesic properties in rodents. Phytochemical and GC–MS analyses confirmed diverse bioactive compounds. MEMPL (200–400 mg/kg) showed anxiolytic, antidepressant, CNS depressant, and antinociceptive effects, comparable to standard drugs.
Tanzil SM, Hakim AA, Islam MT, Tanvir F, Jahan I, Faraque A, Tareq SM, Haque MA, Hossen MA, Faruk MSA, Chowdhury KAA, Islam MN.   +11 more
europepmc   +2 more sources

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

Clinical significance of exercise‐induced hypoalgesia in individuals with temporomandibular disorders and neck pain: A clinical trial protocol

Experimental Physiology, EarlyView.
Abstract Evidence reports positive effects of neck motor control and aerobic exercises (AEs) to improve pain in individuals with temporomandibular disorders (TMD) and neck pain. A single bout of exercise typically leads to an increase in pain thresholds up to 30 min post‐exercise, known as exercise‐induced hypoalgesia (EIH).
Luiz Felipe Tavares, Ana Izabela Sobral de Oliveira‐Souza, Vladimir Aron, Ana Beatriz Oliveira, Henrik Bjarke Vaegter, Susan Armijo‐Olivo   +5 more
wiley   +1 more source

The Performance of Using the Parasympathetic Tone Activity (PTA) Index to Assess Intraoperative Nociception in Cats

Veterinary Sciences
Background: The monitoring of nociception/antinociception poses a significant challenge during anesthesia, making the incorporation of new tools like the Parasympathetic Tone Activity (PTA) monitor an added value in feline anesthesia.
Leonor Lima, José Diogo Dos-Santos, Lénio Ribeiro, Patrícia Cabral, Bruno Colaço, João Martins   +5 more
doaj   +1 more source

Sex Chromosome Complement Affects Nociception and Analgesia in Newborn Mice

, 2008
Laura Gioiosa, Xuqi Chen, Rebecca Watkins, Elizabeth Umeda, Arthur P. Arnold   +4 more
openalex   +2 more sources

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

Experimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela, Anuja R. Bony, Sonia Garcia‐Caraballo, David J. Adams, Stuart M. Brierley   +4 more
wiley   +1 more source