Results 181 to 190 of about 70,074 (346)

Incretin hormones and obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino   +2 more
wiley   +1 more source

Monitoring nociception in patients with morbid obesity undergoing bariatric surgery. [PDF]

open access: yesSaudi J Anaesth
Favitta SF   +4 more
europepmc   +1 more source

Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transient receptor potential ankyrin 1 (TRPA1) and melastatin 3 (TRPM3) activation regulate pre‐ and postsynaptic Ca2+ concentrations and synaptic activity in the dorsal horn of the spinal cord. Left: a model that describes how activation of TRPA1 and TRPM3 channels induces an influx of Ca2+ in the central terminals of sensory ...
Yaroslav E. Andrianov   +10 more
wiley   +1 more source

Neurosteroids in pain management: A new perspective on an old player [PDF]

open access: yes, 2018
Covey, Douglas F   +3 more
core   +2 more sources

5‐HT7 antagonists confer analgesia via suppression of neurotrophin overproduction in submucosal nerves of mouse models with visceral hypersensitivity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram of intestinal nerve abnormality underlying the mechanisms of visceral hypersensitivity. In physiological conditions with normal sensation, enteric neurons are situated in the submucosal and myenteric plexuses, and the spinal afferent fibres ramify within the enteric plexus. However, serotonin/5‐hydroxytryptamine
Tzu‐Yi Lee   +9 more
wiley   +1 more source

Studies on drug dependence (Rept 343): Utility of the (+)TAN-67-induced nociception as a protein kinase C-dependent pain model

open access: gold, 2000
Yoshinori Yajima   +4 more
openalex   +1 more source

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