Results 21 to 30 of about 86,806 (345)
Descending control of nociception in insects?
Proceedings of the Royal Society B, 2022 Modulation of nociception allows animals to optimize chances of survival by adapting their behaviour in different contexts. In mammals, this is executed by neurons from the brain and is referred to as the descending control of nociception.
M. Gibbons, Sajedeh Sarlak, L. Chittka
semanticscholar +1 more source
Pain detection with bioimpedance methodology from 3-dimensional exploration of nociception in a postoperative observational trial [PDF]
, 2020 Although the measurement of dielectric properties of the skin is a long-known tool for assessing the changes caused by nociception, the frequency modulated response has not been considered yet.
Copot, Dana +4 more
core +1 more source
Nociception and pain in humans lacking a functional TRPV1 channel
Journal of Clinical Investigation, 2022 BACKGROUND Chronic pain is a debilitating illness with currently limited therapy, in part due to difficulties in translating treatments derived from animal models to patients.
Ben Katz +12 more
semanticscholar +1 more source
eLife, 2023 Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals ...
Izumi Oikawa +7 more
doaj +1 more source
Frontiers in Systems Neuroscience, 2023 The assessment and management of pain and nociception is very challenging in patients unable to communicate functionally such as patients with disorders of consciousness (DoC) or in locked-in syndrome (LIS).
Estelle A. C. Bonin +17 more
doaj +1 more source
Optogenetics and photopharmacology in pain research and therapeutics
STEMedicine, 2020 Pain afflicts billions of people worldwide, who suffer especially from long-term chronic pain. This gruelling condition affects the nervous system at all levels: from the brain to the spinal cord, the Dorsal Root Ganglia (DRG) and the peripheral fibres ...
Federico Iseppon, Manuel Arcangeletti
doaj +1 more source
Myristic acid reduces skin inflammation and nociception.
Journal of food biochemistry, 2021 This study evaluated the inhibitory effect of myristic acid (MA) on models of inflammation and nociception. The in vitro anti-inflammatory activities of MA were assessed on LPS-stimulated macrophages, membrane stabilization assay, and inhibition of ...
Á. Alonso-Castro +4 more
semanticscholar +1 more source
The ankyrin repeat domain of the TRPA protein painless is important for thermal nociception but not mechanical nociception. [PDF]
PLoS ONE, 2012 The Drosophila TRPA channel Painless is required for the function of polymodal nociceptors which detect noxious heat and noxious mechanical stimuli. These functions of Painless are reminiscent of mammalian TRPA channels that have also been implicated in ...
Richard Y Hwang +2 more
doaj +1 more source
A review on hydrogen sulfide: Is it pro-nociceptive or anti-nociceptive?
İstanbul Journal of Pharmacy, 2022 Pain is sensed by the activation of painful nociceptors in the periphery or by pain mediators, such as bradykinin, serotonin, histamine, and prostaglandin, released from the damaged tissue, afferent transmission to the medulla spinalis, and by trans- mission stages to the high centers over the dorsal horn. Pain, which was seen as only a warning sign in
EKEN, Hazal +2 more
openaire +4 more sources
Quantification of the influence of drugs on zebrafish larvae swimming kinematics and energetics [PDF]
, 2020 The use of zebrafish larvae has aroused wide interest in the medical field for its potential role in the development of new therapies. The larvae grow extremely quickly and the embryos are nearly transparent which allows easy examination of its internal ...
Jiang, Hui-Rong +13 more
core +2 more sources