Results 61 to 70 of about 86,806 (345)
PLoS Neglected Tropical Diseases, 2013 BackgroundThe frequency of accidental spider bites in Brazil is growing, and poisoning due to bites from the spider genus Phoneutria nigriventer is the second most frequent source of such accidents.
Camila Gewehr +9 more
doaj +1 more source
PAIN Reports. Introduction:. The nuclear mitogen- and stress-activated kinases (MSKs) play a critical role in the development and persistence of pain after tissue injury. Objectives:. Here, we ascertained the MSK isoform, the cells and mechanisms, which mediate MSKs'
Jahanzaib Irfan +11 more
doaj +1 more source
Nociceptor-Enriched Genes Required for Normal Thermal Nociception
Cell Reports, 2016 Here, we describe a targeted reverse genetic screen for thermal nociception genes in Drosophila larvae. Using laser capture microdissection and microarray analyses of nociceptive and non-nociceptive neurons, we identified 275 nociceptor-enriched genes ...
Ken Honjo +4 more
doaj +1 more source
Lifting the veil on the keratinocyte contribution to cutaneous nociception
Protein & Cell, 2020 Cutaneous nociception is essential to prevent individuals from sustaining injuries. According to the conventional point of view, the responses to noxious stimuli are thought to be exclusively initiated by sensory neurons, whose activity would be at most ...
M. Talagas +3 more
semanticscholar +1 more source
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior [PDF]
, 2006 The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Baker, MD +8 more
core +1 more source
Nature Communications, 2019 In humans, gamma-band oscillations in the primary somatosensory cortex (S1) correlate with subjective pain perception. However, functional contributions to pain and the nature of underlying circuits are unclear.
L. L. Tan +6 more
semanticscholar +1 more source
Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis
Arthritis Care &Research, EarlyView.Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher +2 more
wiley +1 more source
Analgesia Nociception Index: assessment of acute postoperative pain [PDF]
Revista Brasileira de AnestesiologiaBackground and objectives Patient self-rating based scales such as Numerical Rating Scale, Visual Analog Scale that is used for postoperative pain assessment may be problematic in geriatric or critically ill patients with communication problems. A method
Ruslan Abdullayev +2 more
doaj +3 more sources
TRP Channel Cooperation for Nociception: Therapeutic Opportunities.
Annual Review of Pharmacology and Toxicology, 2020 Chronic pain treatment remains a sore challenge, and in our aging society, the number of patients reporting inadequate pain relief continues to grow. Current treatment options all have their drawbacks, including limited efficacy and the propensity of ...
Dorien Bamps +3 more
semanticscholar +1 more source
Wearable Haptic Feedback Interfaces for Augmenting Human Touch
Advanced Functional Materials, EarlyView.The wearable haptic feedback interfaces enhance user experience in gaming, social media, biomedical instrumentation, and robotics by generating tactile sensations. This review discusses and categorizes current haptic feedback interfaces into force, thermal, and electrotactile stimulation‐based haptic feedback interfaces, elucidating their current ...
Shubham Patel +3 more
wiley +1 more source