Results 71 to 80 of about 70,074 (346)

Directed Self‐Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Magnetically guided bioceramic nanoparticles (“CalBots”) achieve deep dentinal tubule occlusion via directed self‐assembly under externally applied magnetic field. Various visualization techniques and a novel mouse behavioral assay indicate that CalBot‐induced plugs may reduce dentinal sensitivity, offering a promising strategy for future dentin ...
Shanmukh Peddi   +6 more
wiley   +1 more source

Nociception Control of Bilateral Single-Shot Erector Spinae Plane Block Compared to No Block in Open Heart Surgery—A Post Hoc Analysis of the NESP Randomized Controlled Clinical Trial

open access: yesMedicina, 2023
Background and Objectives: The erector spinae plane block (ESPB) is an analgesic adjunct demonstrated to reduce intraoperative opioid consumption within a Nociception Level (NOL) index-directed anesthetic protocol.
Cosmin Balan   +2 more
doaj   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

open access: yesAdvanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang   +28 more
wiley   +1 more source

ION CHANNELS OF NOCICEPTION [PDF]

open access: yesAnnual Review of Physiology, 1999
▪ Abstract  Nociceptors are the first cells in the series of neurons that lead to the sensation of pain. The essential functions of nociceptors—transducing noxious stimuli into depolarizations that trigger action potentials, conducting the action potentials from the peripheral sensory site to the synapse in the central nervous system, and converting ...
Michael S. Gold, Edwin W. McCleskey
openaire   +3 more sources

Toward Autonomous Self‐Healing in Soft Robotics: A Review and Perspective for Future Research

open access: yesAdvanced Intelligent Systems, EarlyView.
In this article, five different phases (damage detection, cleaning, damage closure, material healing, and healing assessment) are investigated to have an autonomous self‐healing at the system level with the focus on soft robotics. It delves into the importance of each phase, why and where they matter, and reviews relevant technologies that enable ...
Seyedreza Kashef Tabrizian   +2 more
wiley   +1 more source

Advances in Invertebrate Biohybrid Robotics: Leveraging Nature for Locomotion and Sensing in Engineered Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
This review explores invertebrate biohybrid robots that integrate living organisms—such as insects, jellyfish, spiders, and sea slugs—into robotic systems for locomotion, sensing, and actuation. The advantages in efficiency and cost, discuss control, and power challenges are highlighted, and future considerations to guide the development of sustainable,
Charles J. Fraga   +2 more
wiley   +1 more source

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani   +6 more
wiley   +1 more source

Analgesia Nociception Index for perioperative analgesia monitoring in spinal surgery

open access: yesRevista Brasileira de Anestesiologia
Background and objectives: The Analgesia Nociception Index is an index used to measure the levels of pain, sympathetic system activity and heart rate variability during general anesthesia.
Guldem Turan   +6 more
doaj   +1 more source

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. [PDF]

open access: yes, 2012
BackgroundResponding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism. The sensations of small and large changes in temperature in most organisms have been studied separately in the context of ...
Ghosh, Rajarshi   +3 more
core   +3 more sources

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