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The endocannabinoid system is thought to modulate nociceptive signaling making it a potential therapeutic target for treating pain. However, there is evidence that endocannabinoids have both pro- and anti-nociceptive effects.
Torrie Summers +3 more
doaj +2 more sources
Nociceptive and tactile information is processed in the somatosensory system via reciprocal (i.e., feedforward and feedback) projections between the thalamus, the primary (S1) and secondary (S2) somatosensory cortices.
Yingchao Song, Rui Zhao, Guotao Yin
exaly +3 more sources
The Role of Nociceptive Neurons in the Pathogenesis of Psoriasis
Psoriasis is a chronic inflammatory skin disease. Emerging evidence shows that neurogenic inflammation, induced by nociceptive neurons and T helper 17 cell (Th17) responses, has a fundamental role in maintaining the changes in the immune system due to ...
Xuan Zhang, Yanling He, He Yanling
exaly +3 more sources
A positive feedback loop between sensory and octopaminergic neurons underlies nociceptive plasticity in Drosophila larvae. [PDF]
Adaptive modulation of nociceptive behaviour based on prior experience is essential for responding effectively to environmental threats. In Drosophila larvae, nociceptive escape behaviours are robust and stereotyped, yet emerging evidence suggests this ...
Jean-Christophe Boivin +5 more
doaj +2 more sources
Nociceptive pain as a clinical presentation of chronic urticaria and disappearance with immunoglobulin/histamine complex therapy: a case report [PDF]
Itching is a representative manifestation of urticaria. However, under certain conditions, urticaria may be characterized by nociceptive sensations, such as stinging or tingling, either instead of or in addition to itching.
Hyuk Soon Kim +4 more
doaj +2 more sources
The role of nociceptive neurons in allergic rhinitis
Allergic rhinitis (AR) is a chronic, non-infectious condition affecting the nasal mucosa, primarily mediated mainly by IgE. Recent studies reveal that AR is intricately associated not only with type 2 immunity but also with neuroimmunity.
Hao Lv, Lv Hao
exaly +3 more sources
Nociception, the sensory mechanism that allows animals to sense and avoid potentially tissue-damaging stimuli, is critical for survival. This process relies on nociceptors, which are specialized neurons that detect and respond to potentially damaging forms of energy - heat, mechanical and chemical - in the environment.
Nathan Risch +2 more
openaire +3 more sources
Recent studies have shown a direct projection of nociceptive trigeminal afferents into the lateral parabrachial nucleus (LPBN). Information about the synaptic connectivity of these afferents may help understand how orofacial nociception is processed in ...
Su Bin An +4 more
doaj +1 more source
Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition
Carpal tunnel syndrome (CTS) has been traditionally classified as primarily a neuropathic condition with or without pain. Precision medicine refers to an evidence-based method of grouping patients based on their susceptibility to biology, prognosis of a ...
César Fernández-de-las-Peñas +7 more
doaj +1 more source
Mechanisms underlying cardiac pain are of major importance in cardiovascular medicine. In this review we address a fundamental clinical and experimental aspect. In particular neural circuitry involved justify a stepwise involvement of central structures responsible of reflex adjustments initiated by peripheral ischemia that can be associated with pain ...
P. G. Camici, M. Pagani
openaire +2 more sources

