Results 31 to 40 of about 97,568 (259)

Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin

open access: yesFrontiers in Immunology, 2021
Bacterial products are able to act on nociceptive neurons during pathogenic infection. Neurogenic inflammation is an active part of pain signaling and has recently been shown to impact host-pathogen defense.
Nicole J. Yang   +7 more
doaj   +1 more source

Immersing the foot in painfully-cold water evokes ipsilateral extracranial vasodilatation [PDF]

open access: yes, 2012
Temporal pulse amplitude was recorded bilaterally in 56 participants before, during and after three ice-water immersions of the foot. Half of the participants were told that prolonged exposure to freezing temperatures could cause frostbite.
Drummond, P.D.   +3 more
core   +1 more source

A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity

open access: yesMarine Drugs, 2013
A novel peptide, RsXXIVA, was isolated from the venom duct of Conus regularis, a worm-hunting species collected in the Sea of Cortez, México. Its primary structure was determined by mass spectrometry and confirmed by automated Edman degradation.
Lourival D. Possani   +10 more
doaj   +1 more source

Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

open access: yesFrontiers in Pharmacology, 2020
The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking.
Takafumi Hayashi   +7 more
doaj   +1 more source

Involvement of A13 dopaminergic neurons located in the zona incerta in nociceptive processing: a fiber photometry study

open access: yesMolecular Brain, 2020
The roles of serotonergic and noradrenergic signaling in nociceptive processing in the central nervous system are well known. However, dopaminergic signaling is also relevant to various physical functions, including nociception.
Shunpei Moriya   +6 more
doaj   +1 more source

Factors Associated With Fibromyalgia Diagnosis Among People Meeting Criteria: Results From UK Biobank

open access: yesArthritis Care &Research, EarlyView.
Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities, and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification.
Sung‐A Kim   +2 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

On‐Skin Wireless Vibratory Interfaces by Stretchable Multilayer Circuits

open access: yesAdvanced Materials Interfaces, EarlyView.
A battery‐free, stretchable wireless vibratory interface is developed through printable liquid‐metal‐based multilayer circuits. The soft device integrates wireless power reception, signal modulation, and vibrotactile actuation within a compliant platform.
Jiawei Liu   +10 more
wiley   +1 more source

The Role of Nociceptive Neurons in the Pathogenesis of Psoriasis

open access: yesFrontiers in Immunology, 2020
Psoriasis is a chronic inflammatory skin disease. Emerging evidence shows that neurogenic inflammation, induced by nociceptive neurons and T helper 17 cell (Th17) responses, has a fundamental role in maintaining the changes in the immune system due to ...
Xuan Zhang, Yanling He
doaj   +1 more source

Excitatory and inhibitory neuronal signaling in inflammatory and diabetic neuropathic pain

open access: yesMolecular Medicine, 2023
Pain, although unpleasant, is an essential warning mechanism against injury and damage of the organism. An intricate network of specialised sensors and transmission systems contributes to reception, transmission and central sensitization of pain.
Ulrike Breitinger, Hans-Georg Breitinger
doaj   +1 more source

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