Results 51 to 60 of about 49,496 (354)
Nanoscale all-oxide-heterostructured bio-inspired optoresponsive nociceptor [PDF]
, 2020 Retina nociceptor, as a key sensory receptor, not only enables the transport of warning signals to the human central nervous system upon its exposure to noxious stimuli, but also triggers the motor response that minimizes potential sensitization. In this
Hu, Jie +4 more
core +2 more sources
Upregulation of TRPM3 in nociceptors innervating inflamed tissue
eLife, 2020 Genetic ablation or pharmacological inhibition of the heat-activated cation channel TRPM3 alleviates inflammatory heat hyperalgesia, but the underlying mechanisms are unknown.
Marie Mulier +7 more
semanticscholar +1 more source
Acta Scientiarum. Health Sciences, 2012 Nervous System Mobilization is used to restore the biomechanics of the nervous system and adjacent structures, promoting the return to their duties. This study evaluated the pain threshold to pressure, to cold, and the cold pain intensity in healthy ...
Anaíma Lopes Frutos +3 more
doaj +1 more source
Mrgprd Enhances Excitability in Specific Populations of Cutaneous Murine Polymodal Nociceptors [PDF]
, 2009 The Mas-related G protein-coupled receptor D (Mrgprd) is selectively expressed in nonpeptidergic nociceptors that innervate the outer layers of mammalian skin.
Anderson, David J. +7 more
core +3 more sources
Chloride – The Underrated Ion in Nociceptors
Frontiers in Neuroscience, 2020 In contrast to pain processing neurons in the spinal cord, where the importance of chloride conductances is already well established, chloride homeostasis in primary afferent neurons has received less attention.
Bettina U. Wilke +3 more
semanticscholar +1 more source
Journal of Neuroscience, 2020 A hyperexcitable state and spontaneous activity of nociceptors have been suggested to play a critical role in the development of chronic neuropathic pain following spinal cord injury (SCI).
Justas Lauzadis +5 more
semanticscholar +1 more source
Biomedicines, 2020 Peripheral nociceptors and their synaptic partners utilize neuropeptides for signal transmission. Such communication tunes the excitatory and inhibitory function of nociceptor-based circuits, eventually contributing to pain modulation.
Haiyan Zheng, J. Lim, J. Seong, S. Hwang
semanticscholar +1 more source
Journal of Neuroscience, 2019 One of the first signs of viral infection is body-wide aches and pain. Although this type of pain usually subsides, at the extreme, viral infections can induce painful neuropathies that can last for decades.
P. Barragán-Iglesias +7 more
semanticscholar +1 more source
European Journal of Pain, 2020 Intradermal injection of 1 µg nerve growth factor (NGF) causes sustained nociceptor sensitization. Slowly depolarizing electrical current preferentially activates C‐nociceptors.
Mark Schnakenberg +3 more
semanticscholar +1 more source
Contribution of Piezo2 to endothelium-dependent pain. [PDF]
, 2015 BackgroundWe evaluated the role of a mechanically-gated ion channel, Piezo2, in mechanical stimulation-induced enhancement of hyperalgesia produced by the pronociceptive vasoactive mediator endothelin-1, an innocuous mechanical stimulus-induced ...
Bogen, Oliver +3 more
core +2 more sources