Results 41 to 50 of about 28,462 (324)
Periosteal nociceptors induced hypotension and bradycardia under spinal anesthesia -A report of two cases- [PDF]
Korean Journal of Anesthesiology, 2011 The sudden hemodynamic disturbance in the perioperative period can occur because of various surgical and anesthetic reasons but hemodynamic collapse due to noxious stimulus of periosteum stripping has not been described.
Rakesh Garg +2 more
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Cutaneous Neuroimmune Interactions in Peripheral Neuropathic Pain States
Frontiers in Immunology, 2021 Bidirectional interplay between the peripheral immune and nervous systems plays a crucial role in maintaining homeostasis and responding to noxious stimuli. This crosstalk is facilitated by a variety of cytokines, inflammatory mediators and neuropeptides.
Daniel B. Lowy +2 more
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Frontiers in Pain ResearchOrthodontic forces are strongly associated with pain, the primary complaint among patients wearing orthodontic braces. Compared to other side effects of orthodontic treatment, orthodontic pain is often overlooked, with limited clinical management ...
Sheng Wang +3 more
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Responses of Cutaneous A-Fiber Nociceptors to Noxious Cold [PDF]
, 1997 Simone, Donald A. and Keith C. Kajander. Responses of cutaneous A fiber nociceptors to noxious cold. J. Neurophysiol. 77: 2049–2060, 1997. Responses of cutaneous nociceptors to natural stimuli, particularly mechanical and heat stimuli, have been well ...
Keith C. Kajander, Donald A. Simone
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Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
Cell Reports, 2021 Summary: Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development.
Mark A. Landy +4 more
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Maximum axonal following frequency separates classes of cutaneous unmyelinated nociceptors in the pig [PDF]
, 2020 Using extracellular single‐fibre recordings from the saphenous nerve in pig in vivo, we investigated peak following frequencies (5–100 Hz) in different classes of C‐nociceptors and their modulation by nerve growth factor. Classes were defined by sensory (
Jørum, Ellen +8 more
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SmartMat, 2023 Artificial synapses and neurons are crucial milestones for neuromorphic computing hardware, and memristors with resistive and threshold switching characteristics are regarded as the most promising candidates for the construction of hardware neural ...
Fu‐Dong Wang +11 more
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Peripheralized sepiapterin reductase inhibition as a safe analgesic therapy
Frontiers in Pharmacology, 2023 The development of novel analgesics for chronic pain in the last 2 decades has proven virtually intractable, typically failing due to lack of efficacy and dose-limiting side effects.
Shane J. F. Cronin +2 more
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Molecular Mechanisms That Contribute to Bone Marrow Pain
Frontiers in Neurology, 2017 Pain associated a bony pathology puts a significant burden on individuals, society, and the health-care systems worldwide. Pathology that involves the bone marrow activates sensory nerve terminal endings of peripheral bone marrow nociceptors, and is the ...
Jason J. Ivanusic
doaj +1 more source
Secondary hyperalgesia is mediated by heat-insensitive A-fibre nociceptors. [PDF]
, 2016 It is believed that secondary hyperalgesia (the increased sensitivity to mechanical nociceptive stimuli that develops after cutaneous tissue injury in the surrounding uninjured skin) is mediated by a subclass of nociceptors: the slowly adapting A-fibre ...
Lenoir, Cédric +2 more
core +1 more source