Results 51 to 60 of about 28,462 (324)

Artificial Adaptive and Maladaptive Sensory Receptors Based on a Surface‐Dominated Diffusive Memristor

open access: yesAdvanced Science, 2022
A biological receptor serves as sensory transduction from an external stimulus to an electrical signal. It allows humans to better match the environment by filtering out repetitive innocuous information and recognize potentially damaging stimuli through ...
Young Geun Song   +10 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

Sensory disturbances in complex regional pain syndrome: Clinical observations, autonomic interactions, and possible mechanisms [PDF]

open access: yes, 2010
To review mechanisms that might contribute to sensory disturbances and sympathetically-maintained pain in complex regional pain syndrome (CRPS). CRPS is associated with a range of sensory and autonomic abnormalities.
Drummond, P.D.
core   +1 more source

Endothelin1 activates and sensitizes human C-nociceptors [PDF]

open access: yes, 2007
Microneurography was used to record action potentials from afferent C-fibers in cutaneous fascicles of the peroneal nerve in healthy volunteers. Afferent fibers were classified according to their mechanical responsiveness to von Frey stimulation (75 g ...
Hilliges, Marita,   +12 more
core   +1 more source

Exploring the Pain-Relieving Potential: Unveiling Antinociceptive Properties in Animal Venoms and Toxins

open access: yesToxins
Currently, commercially available pain medications can cause adverse effects. Within this framework, researchers have been exploring new drug candidates derived from animal venoms and toxins.
Davi Gomes Angstmam   +6 more
doaj   +1 more source

Roles of ASIC3, TRPV1, and Na1.8 in the Transition from Acute to Chronic Pain in a Mouse Model of Fibromyalgia

open access: yesMolecular Pain, 2014
Background: Tissue acidosis is effective in causing chronic muscle pain. However, how muscle nociceptors contribute to the transition from acute to chronic pain is largely unknown.
Wei-Nan Chen   +6 more
doaj   +1 more source

Skin‐Like Tri‐Modal Sensors Based on Soft Piezoelectric and Ionic Composites

open access: yesAdvanced Materials Technologies, EarlyView.
Inspired by the multimodal perception of human skin, a soft, skin‐like tri‐modal sensor is presented. The device incorporates an ionically conductive, piezoelectric, elastic composite as its active layer, enabling independent detection of temperature, static strain, and dynamic strain within a single two‐terminal architecture.
Liren Wang   +9 more
wiley   +1 more source

Deciphering pain: molecular mechanisms and neurochemical pathways–challenges and future opportunities

open access: yesFrontiers in Molecular Biosciences
This review delves into the intricate biological underpinnings of pain perception. It encompasses nociceptive signaling pathways, the molecular mechanisms involved, and the subjective experience of discomfort in humans. The initial focus is on nociceptor
Bahar Dehghan   +3 more
doaj   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

Function and Anatomy of Fast Nociceptors [PDF]

open access: yes
Pain, a fundamental and evolutionarily conserved physiological mechanism, allows organisms to detect and avoid potential harm. In the absence of pain perception (e.g.
Chen, John Chwen-Yu
core   +1 more source

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