Results 81 to 90 of about 49,496 (354)
Contextualized pain management in newborns
Journal of Pediatric and Neonatal Individualized Medicine, 2016 Neonatal pain treatment requires personalization, and pain assessment should be contextualized to be effective. Here we summarize the available tools in neonatal analgesia, paying a special attention to highlight the personalization of antalgic behavior,
Carlo Valerio Bellieni +2 more
doaj +1 more source
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms [PDF]
, 2009 The mechanisms that generate itch are poorly understood at both the molecular and cellular levels despite its clinical importance. To explore the peripheral neuronal mechanisms underlying itch, we assessed the behavioral responses (scratching) produced ...
A. I. Basbaum +32 more
core +2 more sources
Advanced Electronic Materials, EarlyView.A lead‐free perovskite memristive solar cell structure that call emulate both synaptic and neuronal functions controlled by light and electric fields depending on top electrode type. ABSTRACT Memristive devices based on halide perovskites hold strong promise to provide energy‐efficient systems for the Internet of Things (IoT); however, lead (Pb ...
Michalis Loizos +4 more
wiley +1 more source
Antinociceptive modulation by the adhesion GPCR CIRL promotes mechanosensory signal discrimination
eLife, 2020 Adhesion-type GPCRs (aGPCRs) participate in a vast range of physiological processes. Their frequent association with mechanosensitive functions suggests that processing of mechanical stimuli may be a common feature of this receptor family. Previously, we
Sven Dannhäuser +13 more
doaj +1 more source
Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]
, 2018 BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core
, 2003 Pain may appear to undermine the radically intentionalist view that the phenomenal character of any experience is entirely constituted by its representational content. That appearance is illusory.
Bain, D.T.
core +3 more sources
Defining the nociceptor transcriptome [PDF]
Frontiers in Molecular Neuroscience, 2014 Unbiased "omics" techniques, such as next generation RNA-sequencing, can provide entirely novel insights into biological systems. However, cellular heterogeneity presents a significant barrier to analysis and interpretation of these datasets.
Thakur, Matthew +9 more
openaire +4 more sources
Sentience in cephalopod molluscs: an updated assessment
Biological Reviews, EarlyView.ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell +4 more
wiley +1 more source
Molecular Pain, 2011 Background Unmyelinated primary afferent nociceptors are commonly classified into two main functional types: those expressing neuropeptides, and non-peptidergic fibers that bind the lectin IB4.
Clarke Jennifer N +3 more
doaj +1 more source
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]
, 2018 Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L. +39 more
core +2 more sources