Results 91 to 100 of about 22,526 (252)

Nociceptors in antimicrobial defense [PDF]

Nature Immunology, 2020
openaire   +2 more sources

Fish welfare in a changing world: New developments and current challenges

Journal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas, João L. Saraiva, Eliane Gonçalves‐de‐Freitas, Pablo Arechavala‐Lopez, Bernice Bovenkerk, Michael Breen, Steven J. Cooke, Martin Føre, Lene Northwood, Lars Helge Stien, Sunil Kadri, Chris Noble, Jonatan Nilsson, Fernando Rodriguez, Cosme Salas, Peter Sandøe, Hans van de Vis   +16 more
wiley   +1 more source

Cutaneous inflammation alters nociceptor electrophysiology in guinea pigs but not rats

Biomolecules & Biomedicine
Inflammatory pain hypersensitivity is believed to result, in part, from increased excitability of nociceptive dorsal root ganglion (DRG) neurons. We previously demonstrated in guinea pigs that hindlimb inflammation induces electrophysiological changes ...
Laiche Djouhri , Ahmed Eliwa , Alghalya Al-Emadi , Yehia Y. Hussein , Hissa Al-Suwaidi , Al-Jouhara Albaloshi , Ayman Mustafa, Mohammed Seed Ahmed   +7 more
doaj   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

Examining Laterality in Masticatory Myofascial Pain

Journal of Oral Rehabilitation, EarlyView.
Objective: To characterize and compare unilateral and bilateral Masticatory Myofascial Pain (MMP) in a clinical cohort. Methods: Patients with MMP according to the RDC‐TMD were recruited over a 2‐year period. Data were analysed with univariable analyses followed by a binary logistic regression model, with pain laterality as the dependent variable ...
Rafael Benoliel, Yaron Haviv, Shai Levi, Galit Almoznino, Andra Rettman, Yair Sharav   +5 more
wiley   +1 more source

Psychophysical changes after total sleep deprivation and experimental muscle pain

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms.
Emma Hertel, Elaxmi Sathiyalingam, Linea Pilgaard, Simone Juline Brommann, Rocco Giordano, Kristian Kjær‐Staal Petersen   +5 more
wiley   +1 more source

Pain Intensities

Philosophy and Phenomenological Research, EarlyView.
ABSTRACT Recent philosophical work on pain distinguishes a variety of pain qualities and the mechanisms that give rise to them, but pain intensity remains a monolithic notion difficult to account for in reductive terms. The reason for this difficulty is that pain intensity is not a unitary phenomenal magnitude; pain is a complex experience featuring ...
Kim Soland
wiley   +1 more source

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

Periodontology 2000, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin, Troy B. Tran, Paras Ahmad, Nima Farshidfar, Georgios E. Romanos, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

Sex-specific nociceptor modulation of the apical periodontitis transcriptome

Frontiers in Molecular Biosciences
Introduction: Apical periodontitis (AP) is a painful disease that develops quickly following dental infections and is primarily characterized by robust inflammation surrounding the tissues of the affected tooth, resulting in disruption of bone ...
Katherine V. Lillis, Ruta Grinceviciute, Anibal Diogenes   +2 more
doaj   +1 more source