Results 91 to 100 of about 39,802 (268)
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu +3 more
wiley +1 more source
Tenderness and mechanical allodynia are key symptoms of malignant tumor, inflammation and neuropathy. The proinflammatory cytokine interleukin-6 (IL-6) is causally involved in all three pathologies.
Constantin Cristina E +5 more
doaj +1 more source
Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium. [PDF]
IntroductionAcid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis.
Boyle, David L +6 more
core +2 more sources
Abstract Purpose Robotic‐assisted (RA) surgery allows for higher accuracy in total knee arthroplasty (TKA) and for better standardization of alignment concepts. It was hypothesized that the more personalized component placement in functional robotic‐assisted total knee arthroplasty (RA‐TKA) would show an impact on patella mobility and clinical outcome.
Krzysztof Lachowski +5 more
wiley +1 more source
Neural and psychosocial contributions to sex differences in knee osteoarthritic pain
People with osteoarthritis (OA) can have significant pain that interferes with function and quality of life. Women with knee OA have greater pain and greater reductions in function and quality of life than men.
Sluka Kathleen A +11 more
doaj +1 more source
Post-sternotomy pain syndrome following cardiac surgery. case report [PDF]
Over 2 million people undergo sternotomy worldwide for heart surgery each year, and many develop post-sternotomy pain syndrome (PSPS) which persists in the anterior thorax.
Bordoni, Bruno +4 more
core +2 more sources
ABSTRACT Background Vulvar lichen simplex chronicus (VLSC) is a chronic inflammatory dermatosis that remains difficult to manage long term. Fractional CO2 laser (FxCO2) combined with topical corticosteroids (TCs) has emerged as a potential therapeutic strategy; however, high‐quality long‐term evidence remains limited.
Dongmei Wei +6 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
This graphical abstract provides a summary of the analysis of the PACE study that evaluated the effect of high‐concentration capsaicin topical system (HCCTS) on sensory function in patients with DPN. From left to right: Progression of untreated DPN; Research question for current analysis; Outcomes used to evaluate sensory function; Intervention; Main ...
Nathaniel P. Katz +4 more
wiley +1 more source
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source

