Results 81 to 90 of about 28,462 (324)
Calcineurin as a Nociceptor Modulator
Pain Physician, 2009 Calcineurin may be involved in affecting nociceptive processes in multiple circumstances. It is conceivable that interfering with calcineurin’s normal role in contributing to glial resting membrane potential, via its effects on the ion channel (TRESK) [tandem-pore-domain weakly inward rectifying potassium channels (TWIK)-related spinal cord potassium ...
openaire +2 more sources
Developmental Dynamics, EarlyView.Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
Leukotriene B4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat [PDF]
, 1988 1. We have recently shown that leukotriene B4 (LTB4), a product of the 5-lipoxygenase pathway of arachidonic acid metabolism, sensitizes nociceptors to mechanical stimuli.
H. A. Martin +3 more
core +1 more source
Peripheral Deltorphin II Inhibits Nociceptors Following Nerve Injury
Frontiers in Pharmacology, 2020 Clinical and preclinical studies have revealed that local administration of opioid agonists into peripheral tissue attenuates inflammatory pain. However, few studies have examined whether peripherally restricted opioids are effective in reducing ...
Marek Joukal +4 more
doaj +1 more source
Mechanisms regulating excitability of primary afferent nociceptors [PDF]
, 2002 The perception of pain - burning, aching and soreness - acts as a physiological warning that protects us from real or potential injury by employing both behavioural and reflex avoidance responses.
Bikramjit. Chopra (7651850)
core
Catecholamine-induced excitation of nociceptors in sympathetically maintained pain [PDF]
, 2007 Sympathetically maintained pain could either be mediated by ephaptic interactions between sympathetic efferent and afferent nociceptive fibers or by catecholamine-induced activation of nociceptive nerve endings.
Jörum, E. +9 more
core +1 more source
OP0195 TARGETED ABLATION OF KNEE-INNERVATING NOCICEPTORS HAS PROFOUND EFFECTS ON JOINT DAMAGE IN EXPERIMENTAL OSTEOARTHRITIS [PDF]
, 2023 Luwei Wang +5 more
openalex +1 more source
Interdisciplinary Materials, EarlyView.Neuromorphic hardware enables the integration of sensing, memory, and computing for intelligent artificial perception. Recent advances in multimodal fusion further highlight its potential for embodied intelligence and next‐generation human–machine interfaces.
Yixin Zhu +3 more
wiley +1 more source
Response of Cutaneous A- and C-Fiber Nociceptors in the Monkey to Controlled-Force Stimuli [PDF]
, 2000 The goal of this study was to determine the capacity of primary afferent nociceptive fibers (nociceptors) to encode information about noxious mechanical stimuli in primates.
J. N. Campbell, R. M. Slugg, R. A. Meyer
core +1 more source
Organic electrochemical transistor‐based tactile perception: From sensing to neuromorphic processing
InfoMat, EarlyView.Organic electrochemical transistors (OECTs) offer a unique platform for tactile perception electronics by coupling ionic and electronic transport. This review highlights recent advances in OECT‐based temperature and pressure sensing, emphasizing material design, device architectures, operating mechanisms, and fabrication strategies toward flexible ...
Xuefeng Zhang +10 more
wiley +1 more source