Response of Cutaneous A- and C-Fiber Nociceptors in the Monkey to Controlled-Force Stimuli
The goal of this study was to determine the capacity of primary afferent nociceptive fibers (nociceptors) to encode information about noxious mechanical stimuli in primates.
J. N. Campbell, R. M. Slugg, R. A. Meyer
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Silencing Nociceptors Using DREADDs to Improve Functional Outcomes after Spinal Cord Injury [PDF]
A new chemogenetic treatment for inhibition of pain signaling in the peripheral nervous system will be tested using a spinal cord injury model. More than half of spinal cord injury patients experience chronic neuropathic pain that is refractory to ...
Adkins, Robert Lewis
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Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior [PDF]
The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Foulkes, T +8 more
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Catecholamine-induced excitation of nociceptors in sympathetically maintained pain
Sympathetically maintained pain could either be mediated by ephaptic interactions between sympathetic efferent and afferent nociceptive fibers or by catecholamine-induced activation of nociceptive nerve endings.
Jörum, E. +9 more
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Tensile and Compressive Responses of Nociceptors in Rat Hairy Skin
Khalsa, Partap S., Robert H. LaMotte, and Peter Grigg. Tensive and compressive responses of nociceptors in rat hairy skin. J. Neurophysiol. 78: 492–505, 1997.
Robert H. Lamotte +2 more
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Sex-specific nociceptor modulation of the apical periodontitis transcriptome
Introduction: Apical periodontitis (AP) is a painful disease that develops quickly following dental infections and is primarily characterized by robust inflammation surrounding the tissues of the affected tooth, resulting in disruption of bone ...
Katherine V. Lillis +2 more
doaj +1 more source
Epineural optogenetic activation of nociceptors initiates and amplifies inflammation
Activation of nociceptor sensory neurons by noxious stimuli both triggers pain and increases capillary permeability and blood flow to produce neurogenic inflammation(1,2), but whether nociceptors also interact with the immune system remains poorly ...
Tetreault, Michael +18 more
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α-Latrotoxin and Pain: A Nociceptor Perspective on Latrodectism. [PDF]
Davletov B +3 more
europepmc +1 more source
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition. [PDF]
Xu K +13 more
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