Results 61 to 70 of about 20,611 (234)
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Image_2_Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function.jpeg
, 2022 The studies described here provide an analysis of the pathogenesis of Blau syndrome and thereby the function of NOD2 as seen through the lens of its dysfunction resulting from Blau-associated NOD2 mutations in its nucleotide-binding domain (NBD). As such,
Kim Montgomery-Recht (13798072) +8 more
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Indian Pediatrics Case ReportsBackground: Blau syndrome is a monogenic disease resulting from mutations in nucleotide oligomerization domain 2 (NOD2) and is phenotypically characterized by a triad of dermatitis, arthritis, and uveitis.
Suvarna Magar +3 more
doaj +1 more source
PLoS ONE, 2015 Streptococcus (S.) pneumoniae is the most common causative pathogen in community-acquired pneumonia. Nucleotide-binding oligomerization domain-containing (NOD) 2 is a pattern recognition receptor located in the cytosol of myeloid cells that is able to ...
Tijmen J Hommes +7 more
doaj +1 more source
The crosstalk between microbial sensors ELMO1 and NOD2 shape intestinal immune responses
Virulence, 2023 Microbial sensors play an essential role in maintaining cellular homoeostasis. Our knowledge is limited on how microbial sensing helps in differential immune response and its link to inflammatory diseases.
Aditi Sharma +9 more
doaj +1 more source
Current Progress in Differentiating Crohn's Disease From Intestinal Tuberculosis
iLABMED, EarlyView.Currently, there are various methods from different fields used to differentiate Crohn's disease from intestinal tuberculosis (ITB). Endoscopic findings are an important cornerstone. They can be used individually or in combination (models) to demonstrate excellent discriminative ability.
Chuyao Zhang, Xiaoyin Zhang
wiley +1 more source
, 2023 (A) Protein-protein interaction between endogenous LRRK2 and transfected NOD2 by Co-immunoprecipitation (Co-IP). Twenty-four hours post-transfection, cells were left untreated or treated with N-glycolyl MDP (10 μg/ml) for another 24 hours.
Erwin Schurr (238686) +16 more
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Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis. [PDF]
PLoS ONE, 2013 Although the etiology of Crohn's disease (CD) remains elusive this disease is characterized by T cell activation that leads to chronic inflammation and mucosal damage.
Galliano Zanello +5 more
doaj +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba +12 more
wiley +1 more source
, 2014 The fundamental characteristics of mammalian PGLYRPs and NOD2 in the reduction of pathogen-inducedhepatocytic inflammation as well as interaction with probiotics have not yet been well studied.
Meei-Yn Lin, Shiao-Lin Lin, Yi-Heng Chiu
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