Results 91 to 100 of about 188,535 (344)

Portal venous and hepatic artery hemodynamic variation in non-alcoholic fatty liver disease

open access: yesEgyptian Liver Journal, 2021
Background Non-alcoholic fatty liver disease remains asymptomatic until advanced disease, when risk factor modification and available treatment become no longer effective.
Manal Sabry   +5 more
doaj   +1 more source

Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]

open access: yes, 2017
Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J.   +2 more
core   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava   +7 more
wiley   +1 more source

Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease. [PDF]

open access: yesPLoS ONE, 2016
Non-alcoholic fatty liver disease is a prevalent problem throughout the western world. Liver sinusoidal endothelial cells (LSEC) have been shown to play important roles in liver injury and repair, but their role in the underlying pathogenetic mechanisms ...
Rachel H McMahan   +3 more
doaj   +1 more source

Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]

open access: yes, 2019
Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Breaban, Iulia   +10 more
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Betaine chemistry, roles, and potential use in liver disease [PDF]

open access: yes, 2016
Background Betaine is the trimethyl derivative of glycine and is normally present in human plasma due to dietary intake and endogenous synthesis in liver and kidney.
Day, Christopher R., Kempson, Stephen A.
core   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

Metabolically associated fatty liver disease. What is the danger of a "safe" disease? Pathogenesis of cardiovascular complications

open access: yesЛечащий Врач
Background. Nonalcoholic fatty liver disease is most often a latent disease with absent or mild clinical manifestations. It is usually detected as an incidental finding when transaminase levels are elevated or imaging signs of fatty liver degeneration ...
M. A. Isaikina   +2 more
doaj   +1 more source

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