Results 31 to 40 of about 863,687 (283)
Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications. [PDF]
, 2016 Non-coding RNAs are crucial regulators for a vast array of cellular processes and have been implicated in human disease. These biological processes represent a hitherto untapped resource in our fight against disease.
Amy Cording (1383558) +6 more
core +3 more sources
Combined VEGFR and MAPK pathway inhibition in angiosarcoma
Scientific Reports, 2021 Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner +12 more
doaj +1 more source
Erratum: The Non-Coding RNA Journal Club: Highlights on Recent Papers-4. Non-Coding RNA 2016, 2, 9. [PDF]
, 2016 Please note that in the published editorial [1], affiliations 1, and 8 contained errors.[...]
Cuerda-Gil, Diego +9 more
core +3 more sources
Non coding RNA and brain [PDF]
BMC Neuroscience, 2006 Abstract Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, with a wide spectrum of regulatory functions which include RNA modification and regulation of protein synthesis. They have been isolated and characterized in all organisms and tissues, from Archaeobacteria to mammals. In mammalian brain
PRESUTTI, Carlo +3 more
openaire +5 more sources
Scientific Reports, 2017 Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker +4 more
doaj +1 more source
Microbiology Spectrum, 2023 The spread of multidrug resistant and hypervirulent Klebsiella pneumoniae has recently increased. Phages have been considered alternatives for treating infections caused by tenacious pathogens.
Huaixin Geng +7 more
doaj +1 more source
Two genetic codes: Repetitive syntax for active non-coding RNAs; non-repetitive syntax for the DNA archives [PDF]
, 2017 Current knowledge of the RNA world indicates 2 different genetic codes being present throughout the living world. In contrast to non-coding RNAs that are built of repetitive nucleotide syntax, the sequences that serve as templates for proteins share—as ...
Guenther, Witzany
core +1 more source
Non-Coding RNAs and Cancer [PDF]
International Journal of Molecular Sciences, 2013 The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis ...
Calore, Federica +2 more
openaire +2 more sources
Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]
, 2017 Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B +32 more
core +1 more source
Non-Coding RNAs in Glioma [PDF]
Cancers, 2018 Glioma is the most aggressive brain tumor of the central nervous system. The ability of glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained proliferation, and heterogeneity contribute to an overall survival of approximately 15 months for most patients with high grade glioma.
Ryte Rynkeviciene +8 more
openaire +3 more sources