Results 61 to 70 of about 190,163 (275)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Application of Yarrowia lipolytica in fermented beverages

Frontiers in Food Science and Technology, 2023
Yarrowia lipolytica is a non-conventional non-pathogenic, generally regarded as safe yeast. It has been isolated from a wide variety of places, from foodstuffs like beer, cheese and sausages to beetle guts and human mouths.
Anders Bagger Sørensen, Anders Bagger Sørensen, Jesper Harholt, Nils Arneborg   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

New insights into carbon metabolism in Spathaspora passalidarum for second-generation ethanol production

Frontiers in Fungal Biology
Bioethanol is a sustainable, low-impact energy source with the potential to reduce or even replace fossil fuel consumption. Second-generation (2G) bioethanol exploits lignocellulosic agro-industrial residues, contributing to circular economy strategies ...
Sofía Racca, Sofía Racca, Rodrigo J. Leonardi, Rodrigo J. Leonardi, Raúl N. Comelli, Raúl N. Comelli   +5 more
doaj   +1 more source

One-Class-at-a-Time Removal Sequence Planning Method for Multiclass Classification Problems [PDF]

, 2006
Using dynamic programming, this work develops a one-class-at-a-time removal sequence planning method to decompose a multiclass classification problem into a series of two-class problems.
Nagurka, Mark L., Pao, Yi-Hua, Yen, Chen-Wen, Young, Chieh-Neng   +3 more
core   +1 more source

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion [PDF]

, 2009
Mitochondrial fusion requires the coordinated fusion of the outer and inner membranes. Three large GTPases—OPA1 and the mitofusins Mfn1 and Mfn2—are essential for the fusion of mammalian mitochondria.
David C. Chan, J. Michael Mccaffery, Janet M. Shaw, Mariam Ghochani, Terrence G. Frey, Zhiyin Song   +5 more
core   +2 more sources

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Antifungal activity of non-conventional yeasts against Botrytis cinerea and non-Botrytis grape bunch rot fungi

Frontiers in Microbiology, 2022
Grapes harbour a plethora of non-conventional yeast species. Over the past two decades, several of the species have been extensively characterised and their contribution to wine quality is better understood.
Evelyn Maluleke, Neil Paul Jolly, Hugh George Patterton, Mathabatha Evodia Setati   +3 more
doaj   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source