Results 61 to 70 of about 618,873 (254)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Effect of cattle breed on muscle protein quality

open access: yesCzech Journal of Animal Science
The aim of the study was to compare the muscle protein quality in the m. longissimus, pars thoracis of bulls of the Aberdeen Angus (AA) and Czech Fleckvieh (CF) breeds reared under identical conditions within an extensive pasture-based system.
Eva Straková, Natalie Klessy
doaj   +1 more source

The cysteine, total sulfur amino acid, tyrosine, phenylalanine + tyrosine, and non-essential amino acid maintenance requirements of broiler breeders

open access: yesPoultry Science, 2016
Two hundred and fifty Cobb-Vantress broiler breeders were used to determine the maintenance requirement and efficiency of utilization of dietary Cys, Tyr, and non-essential amino acids (AA) in a 21-day experiment. The breeders were fed crystalline amino acid diets containing graded levels of Cys or Tyr representing 0, 10, 20, 30, and 40% of their ...
Ekmay, R. D.   +3 more
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Amino Acid Composition of Tamarind Fruit Growing Wild in Oyo Town

open access: yesFountain Journal of Natural and Applied Sciences (FUJNAS), 2013
Tamarind ( Tamarindus indica L.) fruit grows wild in some parts of the savannah region of Nigeria. The fruit is grossly underutilised in Nigeria, despite its invaluable contribution to the food security and economy of some Asian countries.
A. A. Adeola
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer

open access: yesCancer & Metabolism
Background Amino acids are critical to tumor survival. Tumors can acquire amino acids from the surrounding microenvironment, including the serum. Limiting dietary amino acids is suggested to influence their serum levels.
TashJaé Q. Scales   +10 more
doaj   +1 more source

Characterization of amino acid content of grain of new wheat varieties and lines

open access: yesAgricultural Science and Practice, 2018
Aim. To determine the formation of bound amino acids in grain of new wheat varieties and its biological value. Methods. Field, physical-chemical, computational, analysis. Results.
H. Hospodarenko   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The Role of Proline and Certain Non-Essential Amino Acids in Chick Nutrition

open access: yesPoultry Science, 1962
Abstract THE relative abundance of serine, alanine, aspartic acid and proline in natural proteins has made it difficult to determine their role in chick nutrition when diets containing intact proteins are employed. The dispensable nature of these amino acids in a crystalline amino acid diet was reported by Almquist and Grau (1944).
D.E. Greene   +2 more
openaire   +1 more source

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