Results 131 to 140 of about 15,618,429 (289)
Determination of Selected Essential and Non-Essential Elements in Different Beer Brands of Ethiopia [PDF]
, 2017 The determine amount of selected Mg, Ca, Fe, Cu, Cr, Cd and Pb elements present in different brands of Ethiopian beer available in Ethiopian markets were surveyed, in April 2011. Beer samples were randomly collected from Gondar, Bahir Dar and Woreta town.
Mulugeta, Marye
core +1 more source
Scientific ReportsThere is an increasing concern about the health effects of exposure to a mixture of pollutants. This study aimed to evaluate the associations between serum levels of heavy/essential metals ([Arsenic (As), Cadmium (Cd), Mercury (Hg), Lead (Pb), Nickel (Ni)
Borhan Mansouri +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Biodiminution of lithium in forest floor food webs
Scientific ReportsLithium (Li) is an emerging contaminant of global concern due to its rapidly increasing demand for rechargeable batteries. However, concerns exist regarding its bioaccumulation and trophic transfer in natural food webs, with extremely scarce data ...
Norah Muisa +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2001 Selenium as well as copper, zinc, and manganese play an important role in the detoxification of free radicals. There might be possible interactions with the mechanisms of action for cytostatic drugs as well as ionizing radiation.
Arbeitskreis Trace Elements and Electrolytes in Radiation Oncology (AKTE) (Germany)
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Comparison of breast milk and infant formulas in essential and toxic elements content
, 2017 Background and aim: Human milk is considered to be the best source of nutrition for the newborn infants, and exclusive breastfeeding is recommended by WHO up to 6 months of age.
Marchesi I +7 more
core