Results 91 to 100 of about 60,516 (300)

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Lipid, fatty acid and protein utilization during lecithotrophic larval development of Lithodes santolla (Molina) and Paralomis granulosa (Jacquinot) [PDF]

, 2003
During the larval development of the subantarctic king crab, Lithodes santolla, and stone crab, Paralomis granulosa, we compared changes in the carbon, fatty acid and protein contents of larvae reared under constant conditions from hatching to ...
Kattner, G., Calcagno, J.A., Thatje, S., Graeve, Martin, Lovrich, G.A., Anger, K., Graeve, M., Calcagno, Javier Ángel, Anger, Klaus, Kattner, Gerhard, Lovrich, Gustavo Alejandro, Thatje, Sven, Calcagno, J. A., Lovrich, G. A.   +13 more
core   +1 more source

Calorie intake, body mass, fat mass, tibialis anterior absolute and relative muscle mass, and fasting blood glucose, cholesterol, and non-esterified fatty acid levels.

, 2023
Calorie intake, body mass, fat mass, tibialis anterior absolute and relative muscle mass, and fasting blood glucose, cholesterol, and non-esterified fatty acid levels.
Masayuki Tanaka (67900), Badur un Nisa (17458131), Minoru Tanaka (136513), Sayaka Shimizu (4260112), Roland R. Roy (7826639), Ryosuke Nakanishi (4067659), Noriaki Maeshige (5204432), Hidemi Fujino (5166164), Takumi Hirabayashi (17458134)   +8 more
core   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Metabolic responses to albumin deficiency differ distinctly between partial and full ablation of albumin expression in mice

Lipids in Health and Disease
It had been observed that homozygous albumin knockout mice (Alb −/−) exhibit low plasma free fatty acid (FFA) concentration and improved blood glucose regulation.
Afsoun Abdollahi, Mirandia Szramowski, Keigo Tomoo, Gregory C. Henderson   +3 more
doaj   +1 more source

Impedimetric Detection of Free Fatty Acids in Patient Serum Using Commercially Available Screen-Printed Carbon Electrode

Chemosensors
Objective: The performance of chrono-impedance measurement, a novel electrochemical method for determining free fatty acids (FA), was evaluated in a real-world clinical setting.
İsmail Oran, Halil İbrahim Özdemir, Turgay Yılmaz Kılıç, Hilmiye Deniz Ertuğrul Uygun, Hakan Gökalp Uzun, Barış Kılıçaslan, Evrim Şimşek, Yusuf Ali Altuncı, Şadiye Mıdık, Ali Murat Ergin   +9 more
doaj   +1 more source

Effect of Non-Esterified Fatty Acids on Fatty Acid Metabolism-Related Genes in Calf Hepatocytes Cultured in Vitro

Cellular Physiology and Biochemistry, 2013
Background: NEFA plays numerous roles in the metabolism of glucose, lipids, and proteins. A number of experimental studies have shown that NEFA may have an important role in fatty acid metabolism in the liver, especially in dairy cows that experience ...
Peng Li, Yiming Liu, Yi Zhang, Miao Long, Yang Guo, Zhe Wang, Xinwei Li, Cai Zhang, Xiaobing Li, Jianbin He, Guowen Liu   +10 more
doaj   +1 more source

Effect of the dietary fat quality on insulin sensitivity. [PDF]

, 2008
Recent evidence shows that specific fatty acids affect cell metabolism, modifying the balance between fatty acid oxidation and lipogenesis. These effects may have important implications in addressing the present epidemic of nutrition-related chronic ...
Aguirre, Carolina A, Uauy Dagach-Imbarack, Ricardo, Galgani Fuentes, José, Díaz Bustos, Erik, Aguirre, Carolina A., Galgani, José E, Uauy, Ricardo D, Díaz, Erik O   +7 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Control of Plasma Non-Esterified Fatty Acids in Pregnancy and the Puerperium.

Experimental Biology and Medicine, 1961
SummaryThe amount and timing of glucose administered to fasting post partum women receiving intravenous insulin determines the amount and direction of change in plasma NEFA. Twenty-five grams of glucose inhibits the characteristic response of NEFA to insulin while half this dosage either enhances the insulin effect or causes secondary decrements in non-
R L, BURT, N H, LEAKE, W N, DANNENBURG
openaire   +2 more sources