Results 101 to 110 of about 60,516 (300)

Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells

, 2005
Decreased uncoupling protein (UCP)3 is associated with insulin resistance in muscle of pre-diabetic and diabetic individuals, but the function of UCP3 remains unclear.
Gerrits, Martin F., Wheeler, Michael B., Harper, Mary-Ellen, MacLellan, J. Darcy, Gowing, Adrienne, Smith, Peter J.S.   +5 more
core   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

Advanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li, Di Chang, Jie Yang, Ying Bai, Min Chen, Daoshuang Li, Zuoyu Xu, Jiaxin Yuan, Xiaoxuan Xu, Zhiqi Zhang, Yize Li, Zixin Chen, Jinbing Xie, Zebin Xiao, Shenghong Ju   +14 more
wiley   +1 more source

Metabolic status of crossbreed F1 Holstein × Gyr dairy cows during the transition period in two different seasons in Brazil

Semina: Ciências Agrárias, 2018
Crossbreed F1 Holstein x Gyr cows are proving to be a good alternative for milk production under tropical conditions. In order to contribute to that affirmative, our work focused on clarifying the metabolic patter of F1 Holstein x Gyr dairy cows during ...
Tiago Facury Moreira, Elias Jorge Facury Filho, Anna Luiza Souza Alves Costa Belli, Rodrigo Melo Meneses, Fabíola Oliveira Paes Leme, Jose Azael Zambrano Uribe, Letícia Marques Rodrigues, Antônio Ultimo Carvalho   +7 more
doaj   +1 more source

Chemiluminescecnt determination of serum non-esterified fatty acids.

BUNSEKI KAGAKU, 1988
We have developed a method for chemiluminescent determination of serum non-esterified fatty acids (NEFA) using acyl-CoA synthetase, acyl-CoA oxidase, iso-luminol and micro peroxidase. Since the determination of serum NEFA by the chemiluminescence method was interfered with serum bilirubin, the bilirubin oxidase was used to eliminate the effect of ...
Yosinori UJI, Yoshi SAKAI, Masataka SHIRAKI, Akio NOMA, Masako MAEDA, Akio TSUJI, Hiroaki OKABE   +6 more
openaire   +2 more sources

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Growth inhibition and morphologic changes of HeLa cells exposed to unsaturated fatty acid fraction from the liver of x-ray irradiated rabbits (OX)

, 1962
Biological effect of the unsaturated fatty acid fraction from the X-ray irradiated rabbit liver (OX) on HeLa cells has been observed in vitro comparing with the effect displayed on the same strain cells by the unsaturated fatty acid fraction from the non-
Yamamoto, Michio, Utsumi, Kozo, Seno, Satimaru   +2 more
core   +1 more source

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cellsduring Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

STUDIES ON NON ESTERIFIED FATTY ACID LEVELS IN ORTHOSTIC HYPOTENSION

Nihon Naika Gakkai Zasshi, 1972
起立性低血圧の病態を血漿遊離脂肪酸(NEFA)の面から検討する目的でtilting60°による体位変換を行ない,正常血圧者および各種疾患と対比した.さらに各種起立性低血圧(高血圧性,脳血管性,糖尿病性,特発性)についても検討を行なつた.正常血圧者では, tiltingによりNEFAの上昇がみられたが,起立性低血圧ではtiltingによる交感神経系の反応が欠如し, hypotone型に比し, hypodyname型にNEFAの上昇抑制が著しく,起立による血圧下降の程度とNEFAの上昇抑制とは平行関係が認められた.疾患別では特発性のものでNEFAの抑制が最も強く,糖尿病性においては軽度であつた.さらに人為的に起立性血圧下降を惹起させると,起立性低血圧と同様なNEFAの反応を示した.治療薬として ...
openaire   +2 more sources