Results 121 to 130 of about 60,516 (300)

Effects of fatty acids on inflammatory markers studies in vitro and in vivo

, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery

Angewandte Chemie, EarlyView.
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne, Sona Krajcovicova, Graeme Davies, Hannah Bolt, Jefferson Revell, David R. Spring   +5 more
wiley   +2 more sources

Microflora and grease fleece of normal and felted wool sheep of Ukrainian Carpathian Mountain breed

Біологічні студії
Background. Sheep wool possesses felting properties, which form the basis of felt production. However, felting may also occur directly on the animal, resulting in wool defects.
Vitalii Tkachuk, Nataliia Motko, Nataliia Ohorodnyk, Andriy Boyko, Bogdan Kyryliv   +4 more
doaj   +1 more source

Longitudinal Data to Assess Relationships among Plasma Folate, Vitamin B₁₂, Non-esterified Fatty Acid, and β-Hydroxybutyrate Concentrations of Holstein Cows during the Transition Period. [PDF]

Metabolites, 2023
Duplessis M, Chorfi Y, Girard CL.
europepmc   +1 more source

Fermented Citrus as a Functional Food Matrix: Evaluating Probiotic, Prebiotic, and Postbiotic Potential

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermented citrus transforms bioactive compounds into metabolites with probiotic and prebiotic properties, enhancing gut health, immunity, and metabolic balance. This review highlights fermentation's role in developing sustainable, health‐promoting functional foods while addressing challenges in process optimization, sensory quality, and commercial ...
Sony Kumari, Rahel Debbarma, Shakil Haque, Himalay Baruah   +3 more
wiley   +1 more source

Beneficial effects of 1,3-1,6 β-glucans produced by Aureobasidium pullulans on non-esterified fatty acid levels in diabetic KKAy mice and their potential implications in metabolic dysregulation. [PDF]

J Diabetes Metab Disord, 2023
Ikewaki N, Ikeue Y, Nagataki M, Kurosawa G, Dedeepiya VD, Rajmohan M, Vaddi S, Senthilkumar R, Preethy S, Abraham SJK.   +9 more
europepmc   +1 more source

Effects of fatty acids on inflammatory markers studied in vivo and in vitro

, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core  

Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation [PDF]

, 2000
We tested the hypothesis that excessive portal venous supply of long-chain fatty acids to the liver contributes to the development of insulin resistance via activation of the hypothalamus-pituitary-adrenal axis (HPA axis) and sympathetic system.
Scheurink, AJW, Strubbe, JH, Keizer, Klaasjan,, Kuipers, Folkert,, Kuipers, F, Scheurink, Anton J.W.,, Benthem, L, Kuipers, F; id_orcid, Keizer, Klaas-Jan, Wiegman, Coen H.,, Strubbe, Jan H.,, Boer, Sietse F. de,, Steffens, Anton B.,, Steffens, AB, De Boer, SF, Benthem, Lambertus,, Wiegman, CH   +16 more
core  

Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood

, 2010
Objective: To investigate the relation between breastfeeding, use of docosahexaenoic acid (DHA)-fortified formula and neuropsychological function in children. Design Prospective cohort study. Setting Southampton, UK.
West, C, West, Carolyn, Gale, CR, Limond, Jennifer, Gale, Catharine R., Gale, Catherine R., Martyn, CN, Cooper, Cyrus, Robinson, Sian M., Limond, J, Marriott, Lynne D., Marriott, LD, Inskip, HM, Godfrey, Keith M., Law, Catherine M, Law, CM, Inskip, Hazel M, Martyn, Christopher N., Godfrey, KM, Martyn, Christopher N, Marriott, Lynne D, Inskip, Hazel M., Godfrey, Keith M, Robinson, SM, ?, ?, Robinson, Siân M, Cooper, C   +26 more
core   +1 more source